程序化细胞死亡分子5及其在抗肿瘤研究中的应用
정서화세포사망분자5급기재항종류연구중적응용
Programmed cell death 5 and its application on anti-tumor research
  • 万方数据
    国际肿瘤学杂志 국제종류학잡지
    JOURNAL OF INTERNATIONAL ONCOLOGY
    2011年 6期 418-420 ,共3页

    武成闯%王春晖%王剑松

    무성틈%왕춘휘%왕검송

    PDCD5蛋白%肿瘤%细胞凋亡%药物疗法 PDCD5蛋白%腫瘤%細胞凋亡%藥物療法
    PDCD5단백%종류%세포조망%약물요법
    PDCD5 protein%Neoplasms%Apoptosis%Drug therapy
    程序化细胞死亡分子5(PDCD5)是一种新型促凋亡基因,参与细胞凋亡的调控.研究发现PDCD5在多种肿瘤组织中表达量下调,因而增加PDCD5的表达量呵明显提高化疗药物杀伤肿瘤的敏感性.PDCD5有望成为一种新的化疗增敏剂.
    정서화세포사망분자5(PDCD5)시일충신형촉조망기인,삼여세포조망적조공.연구발현PDCD5재다충종류조직중표체량하조,인이증가PDCD5적표체량가명현제고화료약물살상종류적민감성.PDCD5유망성위일충신적화료증민제.
    Programmed cell death 5(PDCD5)is a novel gene which can promote and regulate apoptosis. The evidences of some studies show that PDCD5 displays reduced expression in a variety of tumor tissue. Increased expression of PDCD5 can improve the sensitivity of anti-tumor chemotherapy. Because of this feature with PDCD5,it is expected to become a new chemosensitizer.
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