CAJ | 학술논문

目的探讨中重度睡眠呼吸暂停低通气综合征(OSAHS)患者白天过度嗜睡(EDS)程度与生活质量的关系.方法选择多导睡眠图(PSG)确诊的中重度OSAHS患者123例为病例组,同期PSG排除OSAHS的良性打鼾患者52例为对照组.以Epworth嗜睡评分(ESS)量表表示患者EDS程度,Calgary生活质量指数(SAQLI)评价中重度OSAHS患者生活质量,比较两组患者一般资料、PSG结果和SAQLI总分及各项评分.结果中重度OSAHS患者与对照组相比,体质量指数(BMI)、呼吸紊乱指数(RDI)、最低氧饱和度( LSpO2)、最长呼吸暂停时间(Tmax)和氧饱和度低于90％时间占总睡眠时间(T90)、ESS评分和SAQLI总分及各项评分等均存在显著性差异.ESS评分与SAQLI总分及各项评分呈显著相关.结论中重度OSAHS患者存在EDS；中重度OSAHS的EDS与生活质量降低有关；EDS可能在一定程度上反映了中重度OSAHS患者的生活质量下降.
목적 탐토중중도수면호흡잠정저통기종합정(OSAHS)환자백천과도기수(EDS)정도여생활질량적관계.방법 선택다도수면도(PSG)학진적중중도OSAHS환자123례위병례조,동기PSG배제OSAHS적량성타한환자52례위대조조.이Epworth기수평분(ESS)량표표시환자EDS정도,Calgary생활질량지수(SAQLI)평개중중도OSAHS환자생활질량,비교량조환자일반자료、PSG결과화SAQLI총분급각항평분.결과 중중도OSAHS환자여대조조상비,체질량지수(BMI)、호흡문란지수(RDI)、최저양포화도( LSpO2)、최장호흡잠정시간(Tmax)화양포화도저우90％시간점총수면시간(T90)、ESS평분화SAQLI총분급각항평분등균존재현저성차이.ESS평분여SAQLI총분급각항평분정현저상관.결론 중중도OSAHS환자존재EDS；중중도OSAHS적EDS여생활질량강저유관；EDS가능재일정정도상반영료중중도OSAHS환자적생활질량하강.
Objective To investigate the association of excessive daytime sleepiness(EDS) and the quality of life in patients with moderate to severe obstructive sleep apnea and hypoventilation syndrome (OSAHS).Methods 123 patients with moderate to severe OSAHS were diagnosed by polysomnography(PSG),and 52 cases ruled out by PSG were controls.Patients and controls were completed the Calgary sleep apnea quality of life index (SAQLI) and the Epworth sleepiness score(ESS).Results There were statistical significance of body mass index (BMI),respiratory disturbance index(RDI),the lowest oxygen saturatioo( LSpO2 ),the longest apnea time( Tmax),the percentage of recording time with oxygen saturation of 90％ or less(T90) between the patients and the controls.Daily Functioning,Social Interactions,Emotional Functioning,Symptoms,and total scores of SAQLI in patients with moderate to severe OSAHS were(3.88 ± 1.05),(4.48 ± 1.39),(4.76 ± 1.59),(2.98 ± 1.10),(3.94 ± 1.22),which were less than that of controls respectively.The ESS scoree of patients with moderate to severe OSAHS were higher than that of controls[ ( 13.98 ± 4.05 ) vs (5.78 ± 2.45) ],( P ＜ 0.01 ).ESS were related to the daily Functioning,social interactions,emotional functioning,symptoms,and total scores of SAQLI in patients with moderate to severe OSAHS,and the coecient of correlation were - 0.52,- 0.48,- 0.40,- 0.48 and - 0.44,respectively,and all p value were less than 0.01.Conclusion Patients with moderate to severe OSAHS have the EDS,which associate with the impairment of quality of life.The higher ESS may indicate the decrease of quality of life in patients with moderate to severe OSAHS.