中华妇产科杂志
中華婦產科雜誌
중화부산과잡지
CHINESE JOUNAL OF OBSTETRICS AND GYNECOLOGY
2012年
7期
514-517
,共4页
孙倩%许静%胡顺琴%陈敏%马润玫%刘子建%张兰%肖雪%钱源%郭知
孫倩%許靜%鬍順琴%陳敏%馬潤玫%劉子建%張蘭%肖雪%錢源%郭知
손천%허정%호순금%진민%마윤매%류자건%장란%초설%전원%곽지
颈部透明带检查%超声检查,产前%妊娠初期%参考值
頸部透明帶檢查%超聲檢查,產前%妊娠初期%參攷值
경부투명대검사%초성검사,산전%임신초기%삼고치
Nuchal translucency measurement%Ultrasonography,prenatal%Pregnancy trimester,first%Reference values
目的 调查昆明地区妊娠早期正常单胎胎儿颈部透明层(NT)厚度的分布情况,制定本地区NT厚度的参考值范围.方法 以2009-2010年在昆明医学院第一附属医院就诊的妊娠早期(孕11 ～ 13周+6)单胎孕妇共1790例为观察对象,参照英国胎儿基金会(FMF)的标准超声测量胎儿头臀径(CRL)及NT厚度,并随访妊娠结局,对确认为正常胎儿的上述测量值通过简单线性回归分析CRL与NT厚度的相关性,制定本地区妊娠早期正常单胎胎儿NT厚度的参考值范围.结果 最终纳入本研究的1790例正常单胎胎儿的CRL均数为(59.6±9.2) mm,中位数为58.3 mm,NT厚度均数为(1.7±0.5) mm,中位数为1.7 mm.不同CRL范围内NT厚度的参考值范围不同,胎儿CRL在45.0～54.9 mm、55.0 ～64.9mm、65.0～74.9 mm、75.0～84.0 mm范围时,相应的NT厚度测量值第5 ～ 95百分位数分别为1.0～2.0 mm、1.3～2.5 mm、1.5 ～2.7 mm、1.5 ～2.9 mm,中位数分别为1.4、1.7、2.0、2.0 mm.胎儿NT厚度测量值与孕妇年龄无显著相关性(P＞0.05)；男胎NT厚度测量值的均数为(1.8±1.1) mm,女胎为(1.7±0.6) mm,两者比较,差异有统计学意义(P =0.001).结论 本研究初步制定出昆明地区妊娠早期正常单胎胎儿不同CRL相对应的NT厚度参考值范围,为产前筛查的进一步实施提供了参考依据.
目的 調查昆明地區妊娠早期正常單胎胎兒頸部透明層(NT)厚度的分佈情況,製定本地區NT厚度的參攷值範圍.方法 以2009-2010年在昆明醫學院第一附屬醫院就診的妊娠早期(孕11 ～ 13週+6)單胎孕婦共1790例為觀察對象,參照英國胎兒基金會(FMF)的標準超聲測量胎兒頭臀徑(CRL)及NT厚度,併隨訪妊娠結跼,對確認為正常胎兒的上述測量值通過簡單線性迴歸分析CRL與NT厚度的相關性,製定本地區妊娠早期正常單胎胎兒NT厚度的參攷值範圍.結果 最終納入本研究的1790例正常單胎胎兒的CRL均數為(59.6±9.2) mm,中位數為58.3 mm,NT厚度均數為(1.7±0.5) mm,中位數為1.7 mm.不同CRL範圍內NT厚度的參攷值範圍不同,胎兒CRL在45.0～54.9 mm、55.0 ～64.9mm、65.0～74.9 mm、75.0～84.0 mm範圍時,相應的NT厚度測量值第5 ～ 95百分位數分彆為1.0～2.0 mm、1.3～2.5 mm、1.5 ～2.7 mm、1.5 ～2.9 mm,中位數分彆為1.4、1.7、2.0、2.0 mm.胎兒NT厚度測量值與孕婦年齡無顯著相關性(P＞0.05)；男胎NT厚度測量值的均數為(1.8±1.1) mm,女胎為(1.7±0.6) mm,兩者比較,差異有統計學意義(P =0.001).結論 本研究初步製定齣昆明地區妊娠早期正常單胎胎兒不同CRL相對應的NT厚度參攷值範圍,為產前篩查的進一步實施提供瞭參攷依據.
목적 조사곤명지구임신조기정상단태태인경부투명층(NT)후도적분포정황,제정본지구NT후도적삼고치범위.방법 이2009-2010년재곤명의학원제일부속의원취진적임신조기(잉11 ～ 13주+6)단태잉부공1790례위관찰대상,삼조영국태인기금회(FMF)적표준초성측량태인두둔경(CRL)급NT후도,병수방임신결국,대학인위정상태인적상술측량치통과간단선성회귀분석CRL여NT후도적상관성,제정본지구임신조기정상단태태인NT후도적삼고치범위.결과 최종납입본연구적1790례정상단태태인적CRL균수위(59.6±9.2) mm,중위수위58.3 mm,NT후도균수위(1.7±0.5) mm,중위수위1.7 mm.불동CRL범위내NT후도적삼고치범위불동,태인CRL재45.0～54.9 mm、55.0 ～64.9mm、65.0～74.9 mm、75.0～84.0 mm범위시,상응적NT후도측량치제5 ～ 95백분위수분별위1.0～2.0 mm、1.3～2.5 mm、1.5 ～2.7 mm、1.5 ～2.9 mm,중위수분별위1.4、1.7、2.0、2.0 mm.태인NT후도측량치여잉부년령무현저상관성(P＞0.05)；남태NT후도측량치적균수위(1.8±1.1) mm,녀태위(1.7±0.6) mm,량자비교,차이유통계학의의(P =0.001).결론 본연구초보제정출곤명지구임신조기정상단태태인불동CRL상대응적NT후도삼고치범위,위산전사사적진일보실시제공료삼고의거.
Objective To establish the normal reference range of fetal nuchal translucency (NT) thickness in Kunming Chinese pregnant women in the first trimester.Methods The study samples comprised of 1790 Kunming pregnant women who attended antenatal visit in the first trimester in the First Affiliated Hospital of Kunming Medical University.The general information including maternal date of birth,past pregnant history and other related conditions were recorded.The crown rump length (CRL) and NT thickness at 11 - 13 +6 gestational weeks were measured according to guidelines from Fetal Medicine Foundation (FMF).Results The total 1790 of normal fetuses was recruited for final analysis.The mean and median values of CRL were (59.6 ± 9.2) mm and 58.3 mm,respectively.The mean and median values of NT thickness were (1.7 ± 0.5 ) mm and 1.7 mm,respectively.While the CRL were at between 45.0 - 54.9 mm,55.0 - 64.9 mm,65.0 - 74.9 mm and 75.0 - 84.0 mm,the corresponding values of NT thickness were 1.0 mm,1.3 mm,1.5 mm,1.5 mm at the 5th percentile and 2.0 mm,2.5 nun,2.7 mm,2.9 mm at the 95th percentile,respectively,and the corresponding medial values of NT thickness were 1.4 mm,1.7 mm,2.0 mm,2.0 mm,respectively.The NT thickness had no relationship with maternal age (P ＞ 0.05).The mean value of NT thickness was ( 1.8 ± 1.1 ) mm in male fetuses.The mean value of NT thickness was ( 1.7 ±0.6) mm in female fetuses.The NT thickness in male fetuses was significantly thicker than that of females ( P = 0.001 ).Conclusion The present study established a reference range of normal fetal NT thickness corresponding with CRL in early pregnancy with reliable FMF quality control.
