CAJ | 학술논문

目的探讨动态亚低温治疗重型颅脑损伤的临床疗效.方法选择自2003年1月至2009年5月四川省人民医院城东病区神经外科收治的重型颅脑损伤患者174例,采用随机数字表法分成动态亚低温组(A组)、亚低温短时程组(B组)及常温治疗组(C组),比较其临床疗效及并发症.结果 A组有效率为84.48,死亡率为8.62%;B组有效率为67.24,死亡率为15.51%:C组有效率为48.27,死亡率为36.20%;3组有效率差异有统计学意义(P<0.05).总并发症3组比较差异无统计学意义(P>0.05).结论根据重型颅脑损伤患者个体化差异采取亚低温动态化治疗,能有效提高治疗有效率,且并发症不会增加.
목적 탐토동태아저온치료중형로뇌손상적림상료효.방법 선택자2003년1월지2009년5월사천성인민의원성동병구신경외과수치적중형로뇌손상환자174례,채용수궤수자표법분성동태아저온조(A조)、아저온단시정조(B조)급상온치료조(C조),비교기림상료효급병발증.결과 A조유효솔위84.48,사망솔위8.62%;B조유효솔위67.24,사망솔위15.51%:C조유효솔위48.27,사망솔위36.20%;3조유효솔차이유통계학의의(P<0.05).총병발증3조비교차이무통계학의의(P>0.05).결론 근거중형로뇌손상환자개체화차이채취아저온동태화치료,능유효제고치료유효솔,차병발증불회증가.
Objective To investigate the clinical effects of dynamic mild hypothermia on patients with severe brain injury. Methods One hundred and seventy-four patients with severe brain injury, admitted to our hospital from 2003 to 2009, were chosen and randomly assigned to mild hypothermia treatment group, short-term mild hypothermia treatment group and control group; their clinical outcomes and complications were recorded. Results The difference on effective rate of the 3 groups was significant (84.48%, 67.24%, 48.27%, respectively, P<0.05); the mortality in the 3 groups was 8.62%, 15.51%, 36.20%, respectively. No significant difference of complications was showed in the 3 groups (46.55%, 46.55% and 48.27%, respectively, P>0.05). Conclusion Dynamic mild hypothermia therapy can improve the outcomes of severe brain injury according to the patients' condition.