CAJ | 학술논문

持续性心房颤动(房颤)患者216例根据房颤血栓栓塞危险分层CHADS2评估系统评分,分别按0～6分逐一分组,是否≥2分分为两组,应用经颅多普勒检查微栓子及免疫比浊法测定D-二聚体.结果显示,随CHADS2评分分值增加,监测到的微栓子数量及D-二聚体水平有增加趋势,0分、1分组微栓子数量及D-二聚体水平显著低于其他高分值组(P＜0.05),5分、6分组微栓子数量显著高于其他分值组(P＜0.05)；CHADS2评分≥2分组微栓子检出数量及D-二聚体水平显著高于＜2分组(P＜0.01).提示,微栓子及血浆D-二聚体水平可反映房颤患者发生血栓栓塞的危险性.
지속성심방전동(방전)환자216례근거방전혈전전새위험분층CHADS2평고계통평분,분별안0～6분축일분조,시부≥2분분위량조,응용경로다보륵검사미전자급면역비탁법측정D-이취체.결과현시,수CHADS2평분분치증가,감측도적미전자수량급D-이취체수평유증가추세,0분、1분조미전자수량급D-이취체수평현저저우기타고분치조(P＜0.05),5분、6분조미전자수량현저고우기타분치조(P＜0.05)；CHADS2평분≥2분조미전자검출수량급D-이취체수평현저고우＜2분조(P＜0.01).제시,미전자급혈장D-이취체수평가반영방전환자발생혈전전새적위험성.
To observe the D-dimer levels and the numbers of micro-embolic signals (MES) in atrial fibrillation patients with different thromboembolic risk scores. A total of 216 persistent atrial patients were classified according to their different scores with a range of 0 -6.They were also divided into two groups by ≥2 or ＜ 2 according to the CardiacFailure,Hypertension,Age,Diabetes,Stroke 2 (CHADS2) point system.D-dimer levels and the numbers of MES were detected in all patients.A rising trend of D-dimer level and the number of MES was observed with the increases of CHADS2 score. D-dimer level and the number of MES in group 0 or 1 score were significantly lower than those in other high score groups (P ＜ 0.05).And the number of MES in group 5 or 6 score was significantly higher than those in other low score groups (P ＜ 0.05).D-dimer level and the number of MES in the group of ≥ 2 score were significantly higher than those in group ＜ 2 score ( P ＜ 0.01 ).It suggests that D-dimer level and the nunber of MES may reflect the thromboembolic risks in atrial fibrillation patients.