中国临床实用医学
中國臨床實用醫學
중국림상실용의학
CHINA CLINICAL PRACTICAL MEDICINE
2010年
12期
61-62
,共2页
张丽娜%刘炳波%于泳%刘伟
張麗娜%劉炳波%于泳%劉偉
장려나%류병파%우영%류위
玻璃酸钠%滴鼻液%制备%质量控制
玻璃痠鈉%滴鼻液%製備%質量控製
파리산납%적비액%제비%질량공제
Sodium hyaluronate%Nose drops%Preparation%Quality control
目的 研制呋麻缓释滴鼻液,用于耳鼻喉科缓解急、慢性鼻炎的鼻塞症状.方法 制定呋麻缓释滴鼻液制备工艺,并考察该制剂的稳定性、疗效.结果 该制剂稳定性实验显示与对照组比较无差异,室温放置后其性状、色泽、含量及pH等无显著变化.结论 呋麻缓释滴鼻液在鼻腔内滞留时间长,药效好,安全性好.
目的 研製呋痳緩釋滴鼻液,用于耳鼻喉科緩解急、慢性鼻炎的鼻塞癥狀.方法 製定呋痳緩釋滴鼻液製備工藝,併攷察該製劑的穩定性、療效.結果 該製劑穩定性實驗顯示與對照組比較無差異,室溫放置後其性狀、色澤、含量及pH等無顯著變化.結論 呋痳緩釋滴鼻液在鼻腔內滯留時間長,藥效好,安全性好.
목적 연제부마완석적비액,용우이비후과완해급、만성비염적비새증상.방법 제정부마완석적비액제비공예,병고찰해제제적은정성、료효.결과 해제제은정성실험현시여대조조비교무차이,실온방치후기성상、색택、함량급pH등무현저변화.결론 부마완석적비액재비강내체류시간장,약효호,안전성호.
Objective To develop ephedrine hydrochloride and nitrofurazone release nasal drops and to investigate the effects of relieving nasal congestion in acnte and chronic rhinitis. Methods To draw up the preparation technology of ephedrine hydrochloride and nitrofurazone release nasal drops, studying the stability of the preparation. Results The preparation was no difference with the control group by stability experiment. Af-ter room temperature, the character, color, content and pH was no significant change. Conclusion Ephedrine hydrochloride and nitrofurazone release nasal drops has a long residence tine in the nasal cavity, good efficacy and safety.