中国临床实用医学
中國臨床實用醫學
중국림상실용의학
CHINA CLINICAL PRACTICAL MEDICINE
2010年
6期
65-66
,共2页
雷公藤多甙%福辛普利%肾病综合征型紫癜性肾炎
雷公籐多甙%福辛普利%腎病綜閤徵型紫癜性腎炎
뢰공등다대%복신보리%신병종합정형자전성신염
Tripterygium wilfordii polypeptide%Fosinopril%Nephrotic syndrome Henoch-Schonlein nephritis
目的 观察雷公藤多甙联合福辛普利治疗儿童肾病综合征型紫癜性肾炎的治疗效果.方法 2006年12月至2009年12月在我院儿科就诊的38例诊断为肾病综合征型紫癜性肾炎的患儿,分别将患儿随机分为治疗组20例(口服雷公藤多甙联合福辛普利)和对照组18例(口服雷公藤多甙),观察药物对两组患儿水肿、高血压、血尿、蛋白尿的疗效,采用SPSS10.0软件进行统计学分析.结果 治疗组完全缓解18例(90%),部分缓解2例(10%).对照组完全缓解11例(61%),部分缓解6例(39%),无效1例(6%)两组缓解率比较,差异无显著性(P＞0.05),但治疗组水肿消退、血压恢复正常、血尿消失、尿蛋白转阴的平均时间均明显短于对照组,差异有显著性(P＜0.01).结论 雷公藤多甙联合福辛普利治疗儿童肾病综合征型紫癜性肾炎疗效优于单用雷公藤多甙,值得临床应用.
目的 觀察雷公籐多甙聯閤福辛普利治療兒童腎病綜閤徵型紫癜性腎炎的治療效果.方法 2006年12月至2009年12月在我院兒科就診的38例診斷為腎病綜閤徵型紫癜性腎炎的患兒,分彆將患兒隨機分為治療組20例(口服雷公籐多甙聯閤福辛普利)和對照組18例(口服雷公籐多甙),觀察藥物對兩組患兒水腫、高血壓、血尿、蛋白尿的療效,採用SPSS10.0軟件進行統計學分析.結果 治療組完全緩解18例(90%),部分緩解2例(10%).對照組完全緩解11例(61%),部分緩解6例(39%),無效1例(6%)兩組緩解率比較,差異無顯著性(P＞0.05),但治療組水腫消退、血壓恢複正常、血尿消失、尿蛋白轉陰的平均時間均明顯短于對照組,差異有顯著性(P＜0.01).結論 雷公籐多甙聯閤福辛普利治療兒童腎病綜閤徵型紫癜性腎炎療效優于單用雷公籐多甙,值得臨床應用.
목적 관찰뢰공등다대연합복신보리치료인동신병종합정형자전성신염적치료효과.방법 2006년12월지2009년12월재아원인과취진적38례진단위신병종합정형자전성신염적환인,분별장환인수궤분위치료조20례(구복뢰공등다대연합복신보리)화대조조18례(구복뢰공등다대),관찰약물대량조환인수종、고혈압、혈뇨、단백뇨적료효,채용SPSS10.0연건진행통계학분석.결과 치료조완전완해18례(90%),부분완해2례(10%).대조조완전완해11례(61%),부분완해6례(39%),무효1례(6%)량조완해솔비교,차이무현저성(P＞0.05),단치료조수종소퇴、혈압회복정상、혈뇨소실、뇨단백전음적평균시간균명현단우대조조,차이유현저성(P＜0.01).결론 뢰공등다대연합복신보리치료인동신병종합정형자전성신염료효우우단용뢰공등다대,치득림상응용.
Objective To observe tripterygium wilfordii polypeptide (TWP)combined fosinopril treatment of children with nephrotic syndrome treatment of Henoch-Schonlein purpura nephritis. Methods from December 2006 to December 2009 in our hospital pediatric clinic, 38 patients were diagnosed as nephrotic syndrome in children with Henoch-Schonlein Purpura nephritis, respectively, were randomly divided into treatment group(20 cases of oral TWP joint Fosinopril)and control group, 18 patients( oral TWP) , observation of drugs on two groups of children with edema, hypertension, hematuria, proteinuria efficacy, using SPSS10. 0 software for statistical analysis. Results The complete remission in 18 cases ( 90% ), partial remission in 2 cases (10%). Control group, complete remission in 11 cases(61% ), partial remission in 6 cases(39% ), ineffective in 1 (6%)remission rate of the two groups, the difference was not significant( P ＞ 0. 05 ), but the treatment group edema subsided, blood pressure returned to normal, hematuria disappeared, urine protein was negative on average were significantly shorter than the control group, the difference was significant (P ＜ 0. 01 ).Conclusion The effect of TWP combined fosinopril treatment of children with nephrotic syndrome HenochSchonlein purpura nephritis is better than TWP alone and it is worth clinical application.
