CAJ | 학술논문

目的探讨P16蛋白的表达与食管癌恶性潜能和进展密切相关.方法检测56例食管癌患者癌组织P16的表达,并进行随访.结果 P16蛋白表达阳性率越低,食管癌术后生存率也越代,反之也然.结论 P16蛋白表达率能较好地反映食管癌预后,P16表达缺失或下调是食管癌恶性潜能和进展晚期的一种特异表现.P16蛋白表达与食管癌患者预后有一定的关系.
목적 탐토P16단백적표체여식관암악성잠능화진전밀절상관.방법 검측56례식관암환자암조직P16적표체,병진행수방.결과 P16단백표체양성솔월저,식관암술후생존솔야월대,반지야연.결론 P16단백표체솔능교호지반영식관암예후,P16표체결실혹하조시식관암악성잠능화진전만기적일충특이표현.P16단백표체여식관암환자예후유일정적관계.
Objective Previons studies showed that,the gene of P16 is a kind of gene suppressing the cancer.its function once lose,the cell may change to cancer.Methods The expression of P16 has a closely relation with the malignant latent and evolve of the oesophagus cancer.ResulIs This research explored the relation between the P16 expression and the prognosis of oesophagus cancer,the results showed the positive rate of the expression of P16 is more low the rate ofexistence is more low,it in dicates the expression rate of P16 can reflect the prognosis of oesophagus cancer cell.Conclusion The expression of P16 missing or descending is closely rehted with the aggravate and evolve of oesophagus cancer,therefore the expression of P16 had a relation with the prognosis of oesophagus cancer.