CAJ | 학술논문

目的探讨不同时间的吸氧排氮方案对高空减压病的预防效果.方法 24只家兔随机分为对照组、吸氧排氮30、60和120 min组4组.麻醉后行机械通气,分别吸氧排氮0、30、60和120 min后上升至11 000 m停留30 min,用超声多普勒技术检测气泡产生情况.结果高空减压时气泡首次检出时间随着吸氧排氮时间的增加而延长,吸氧排氮60 min和120 min组家兔气泡首次检出时间较对照组显著延长(P<0.01),气泡首次检出时间与吸氧排氮时间呈正相关关系(P<0.01); 累积气泡数随着吸氧排氮时间的增加而减少,吸氧排氮60 min和120 min组家兔累积气泡数较对照组显著减少(P<0.01),累积气泡数与吸氧排氮时间呈负相关关系(P<0.01).结论吸氧排氮60 min和120 min两种方案可以显著减少兔由地面上升到11 000 m高空减压时气泡的产生.
목적탐토불동시간적흡양배담방안대고공감압병적예방효과.방법 24지가토수궤분위대조조、흡양배담30、60화120 min조4조.마취후행궤계통기,분별흡양배담0、30、60화120 min후상승지11 000 m정류30 min,용초성다보륵기술검측기포산생정황.결과고공감압시기포수차검출시간수착흡양배담시간적증가이연장,흡양배담60 min화120 min조가토기포수차검출시간교대조조현저연장(P<0.01),기포수차검출시간여흡양배담시간정정상관관계(P<0.01); 루적기포수수착흡양배담시간적증가이감소,흡양배담60 min화120 min조가토루적기포수교대조조현저감소(P<0.01),루적기포수여흡양배담시간정부상관관계(P<0.01).결론흡양배담60 min화120 min량충방안가이현저감소토유지면상승도11 000 m고공감압시기포적산생.
Objective To explore the effect of different degrees of denitrogenation on decompression sickness. Method Twenty-four rabbits were randomly divided into control group, 100% oxygen inhalation 30 min group, 60 min group and 120 min group. The rabbits were anesthetized and ventilated by mechanical ventilator. After 0, 30, 60 and 120 min of denitrogenation by inhalation of 100% oxygen, the rabbits were exposed to 11 000 m for 30 min. The gas bubbles generated in the body of rabbits were detected and monitored by a Doppler ultrasound detector over the precordium. Result Time to bubble appearance increased with time of 100% oxygen inhalation during altitude decompression. As compared with the control group, time to bubble appearance lengthened significantly in 100% oxygen inhalation 60 min and 120 min groups (P<0.01). Time to bubble appearance was positively correlated with time of 100% oxygen inhalation (P<0.01). Accumulative number of bubbles decreased with the time of 100% oxygen inhalation. As compared with the control group, accumulative number of bubbles decreased significantly in 100% oxygen inhalation 60 min and 120 min groups (P<0.01). Accumulative number of bubbles was negatively correlated with time of 100% oxygen inhalation (P<0.01). Conclusion Denitrogenation by inhalation of 100% oxygen for 60 min and 120 min may reduce the generation of gas bubbles in rabbits when decompressed to an altitude of 11 000 m.