CAJ | 학술논문

目的:观察卡托普利联合胺碘酮治疗老年高血压伴阵发性心房颤动(房颤)患者的疗效.方法:将70例老年高血压伴阵发性房颤患者随机分为胺碘酮组和联合用药组(卡托普利联合胺碘酮),治疗12个月,计算两组治疗后第3、6、9、12个月的窦性心律维持率和治疗前及治疗后第6、12个月的左心房内径.结果:研究期结束后各组内治疗前后血压变化比较具有显著性,但两组间治疗后血压无显著性差异.治疗后9、12个月,联合用药组的窦性心律维持率显著高于胺碘酮组.两组间左心房内径在治疗后12个月时胺碘酮组显著高于联合用药组.结论:卡托普利联合胺碘酮治疗老年高血压伴阵发性房颤,可抑制左房扩大,并有效预防房颤复发.
목적:관찰잡탁보리연합알전동치료노년고혈압반진발성심방전동(방전)환자적료효.방법:장70례노년고혈압반진발성방전환자수궤분위알전동조화연합용약조(잡탁보리연합알전동),치료12개월,계산량조치료후제3、6、9、12개월적두성심률유지솔화치료전급치료후제6、12개월적좌심방내경.결과:연구기결속후각조내치료전후혈압변화비교구유현저성,단량조간치료후혈압무현저성차이.치료후9、12개월,연합용약조적두성심률유지솔현저고우알전동조.량조간좌심방내경재치료후12개월시알전동조현저고우연합용약조.결론:잡탁보리연합알전동치료노년고혈압반진발성방전,가억제좌방확대,병유효예방방전복발.
Objective: To evaluate the treatment of Captopril and Amiodarone to cure the elder hypertension and paroxysmal atrial fibrillation. Methods: 70 cases of elderly hypertensive patients with paroxysmal atrial fibrillation were randomly divided into Amiodarone group and combination group (Captopril combined Amiodarone), they were treated of 12 months, the rhythm control of the two groups after treatment 3, 6, 9,12 months and the left atrial diameter after treatment 6, 12 months were calculated. Results: There were significant changes of the blood pressure after treatment in each group, but no significant difference between two groups. The rate of rhythm control of the combination group was significant higher than that of the Amiodarone group after 9 and 12 months treatment. The change of the left atrial diameter was significant between the two groups after 12 months treatment. Conclusion: Captopfil combined with Amiodarone can decrease the blood pressure, inhibit left atrial enlargement and effective in preventing recurrence of atrial fibrillation in elderly hypertensive paroxysmal atrial fibrillation.