CAJ | 학술논문

将研究重点从单个基因转移到基因信号通路,结合随机森林与信号通路分析了一组胃癌微阵列数据.通过研究基因在通路中的情况以及通路中的基因对胃癌肠型、弥漫型和正常组织样本的分类能力,扩展了随机森林在生物学中的应用,为胃癌的研究提供了新的思路.
장연구중점종단개기인전이도기인신호통로,결합수궤삼림여신호통로분석료일조위암미진렬수거.통과연구기인재통로중적정황이급통로중적기인대위암장형、미만형화정상조직양본적분류능력,확전료수궤삼림재생물학중적응용,위위암적연구제공료신적사로.
The focus from single-gene to gene signal pathway was transferred and combined random forests method with gene pathway to analyze gastric cancer microarray data. According to research,the genes above pathway level as well as classifying capability of genes in pathways for different subtypes,intestinal and diffuse,and normal tissues of gastric cancer,the application of RF in biology were concerned,and a new thought for studies of gastric cancer was provided.