中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2010年
8期
1068-1070
,共3页
哮喘%肺功能
哮喘%肺功能
효천%폐공능
Asthma%Pulmonary function
目的 比较两种方法治疗支气管哮喘患儿的疗效.方法 100例支气管哮喘患儿按住院单双号分成治疗组50例和对照组50例,治疗组每天吸入沙美特罗/氟替卡松粉吸入剂,每次50/100 μg;对照组每天吸入丙酸氟替卡松吸入剂,每次100μg.所有病例分别于治疗后4、12周后,观察第一秒时间肺活量(FEVl)、呼气峰流速(PEF)、肺活量25%的瞬时流速(V75)、肺活量50%的瞬时流速(V50)、肺活量75%的瞬时流速(V25)及其占预计值的百分比.结果 治疗4周后治疗组总有效43例(86.0%)高于对照组的28例(56.5%)(x~2=3.987,P＜0.05);治疗后12周两组患儿FEVI和PEF占预计值百分比较治疗前明显升高(x~2=4.01、4.21、4.31、4.08,均P＜0.05),组间比较无统计学意义(x~2=2.31、2.41,均P＞0.05);两组治疗12周后V75、V50、V25分别达到了预计值的90%以上,两组治疗后V75、V50、V25与治疗前比较,改善明显(x~2=4.285、4.234、4.311、4.278,均P＜0.05).结论 两种方法治疗支气管哮喘疗效肯定,沙美特罗/氟替卡松粉吸入剂治疗支气管哮喘疗效更佳.
目的 比較兩種方法治療支氣管哮喘患兒的療效.方法 100例支氣管哮喘患兒按住院單雙號分成治療組50例和對照組50例,治療組每天吸入沙美特囉/氟替卡鬆粉吸入劑,每次50/100 μg;對照組每天吸入丙痠氟替卡鬆吸入劑,每次100μg.所有病例分彆于治療後4、12週後,觀察第一秒時間肺活量(FEVl)、呼氣峰流速(PEF)、肺活量25%的瞬時流速(V75)、肺活量50%的瞬時流速(V50)、肺活量75%的瞬時流速(V25)及其佔預計值的百分比.結果 治療4週後治療組總有效43例(86.0%)高于對照組的28例(56.5%)(x~2=3.987,P＜0.05);治療後12週兩組患兒FEVI和PEF佔預計值百分比較治療前明顯升高(x~2=4.01、4.21、4.31、4.08,均P＜0.05),組間比較無統計學意義(x~2=2.31、2.41,均P＞0.05);兩組治療12週後V75、V50、V25分彆達到瞭預計值的90%以上,兩組治療後V75、V50、V25與治療前比較,改善明顯(x~2=4.285、4.234、4.311、4.278,均P＜0.05).結論 兩種方法治療支氣管哮喘療效肯定,沙美特囉/氟替卡鬆粉吸入劑治療支氣管哮喘療效更佳.
목적 비교량충방법치료지기관효천환인적료효.방법 100례지기관효천환인안주원단쌍호분성치료조50례화대조조50례,치료조매천흡입사미특라/불체잡송분흡입제,매차50/100 μg;대조조매천흡입병산불체잡송흡입제,매차100μg.소유병례분별우치료후4、12주후,관찰제일초시간폐활량(FEVl)、호기봉류속(PEF)、폐활량25%적순시류속(V75)、폐활량50%적순시류속(V50)、폐활량75%적순시류속(V25)급기점예계치적백분비.결과 치료4주후치료조총유효43례(86.0%)고우대조조적28례(56.5%)(x~2=3.987,P＜0.05);치료후12주량조환인FEVI화PEF점예계치백분비교치료전명현승고(x~2=4.01、4.21、4.31、4.08,균P＜0.05),조간비교무통계학의의(x~2=2.31、2.41,균P＞0.05);량조치료12주후V75、V50、V25분별체도료예계치적90%이상,량조치료후V75、V50、V25여치료전비교,개선명현(x~2=4.285、4.234、4.311、4.278,균P＜0.05).결론 량충방법치료지기관효천료효긍정,사미특라/불체잡송분흡입제치료지기관효천료효경가.
Objective To investigate curative effect in children with bronchial asthma by two treatment methods. Methods 100 children with bronchial asthma,according to the different treatment were divided into treatment group 50 cases and control group(50 cases). The first seconds vital capacity(FEV1),peak expiratory flow (PEF) ,vital capacity 25% of the instantaneous velocity (V75), vital capacity 50% of the instantaneous velocity (V50) ,vital capacity 75% of the instantaneous velocity(V25) and their percentage the percentage of predicted value were observed. Results Total effective of 43 cases(86.0%) in treatment group after treatment 4 weeks were higher than that in control group of 28 cases (56. 5 %) (x~2 = 3. 987, P ＜ 0.05); The percentage of FEV1 and PEF in two groups after treatment 12 weeks were significantly higher than that before treatment(x~2 = 4. 01,4. 21,4. 31,4. 08, all P ＜ 0.05), but it between the two groups was not statistically significant (x~2 = 2. 31,2. 41, all P ＞ 0.05); The pulmonary function of V75 、V50、V25 in two groups after treatment 12 weeks reached projected value of more than 90% ;The pulmonary function of V75 、V50、V25 after treatment compared with those before treatment were improved significantly (x~2 =4.285,4.234,4.311,4.278,all P＜0.05). Conclusion The curative effect of bronchial asthma were confirmed in two methods,but treatment group were better than the control group.
