国际儿科学杂志
國際兒科學雜誌
국제인과학잡지
INTERNATIONAL JOURNAL OF PEDIATRICS
2011年
4期
397-399
,共3页
CD133分子%造血干细胞%白血病干细胞
CD133分子%造血榦細胞%白血病榦細胞
CD133분자%조혈간세포%백혈병간세포
CD133 molecule%Hematopoietic stem cells%Leukemic stem cells
CD133分子是一种新的造血干细胞标志,可能是某些肿瘤的肿瘤干细胞标志.目前,有关CD133的研究多关注在CD133-1上,而CD133-2与CD133-1的关系研究较少.该文聚焦于CD133这两类亚型分子,以便有效地提高其针对性,并有可能进一步区分造血干细胞与白血病干细胞,为白血病的靶向治疗提供理论和实验基础.
CD133分子是一種新的造血榦細胞標誌,可能是某些腫瘤的腫瘤榦細胞標誌.目前,有關CD133的研究多關註在CD133-1上,而CD133-2與CD133-1的關繫研究較少.該文聚焦于CD133這兩類亞型分子,以便有效地提高其針對性,併有可能進一步區分造血榦細胞與白血病榦細胞,為白血病的靶嚮治療提供理論和實驗基礎.
CD133분자시일충신적조혈간세포표지,가능시모사종류적종류간세포표지.목전,유관CD133적연구다관주재CD133-1상,이CD133-2여CD133-1적관계연구교소.해문취초우CD133저량류아형분자,이편유효지제고기침대성,병유가능진일보구분조혈간세포여백혈병간세포,위백혈병적파향치료제공이론화실험기출.
CD133 molecule is a new symbol of hematopoietic stem cells ( HSC). It may be a symbol of cancer stem cells in some cancer. Up to now, CD133 - 1 molecule has been paid close attention to in much literature . But research of their relationship between CD133-1 and CD 133-2 has little. The study will focus on two different CD133 molecule so that HSC and leukemic stem cells can be distinguished with using subgroup molecule. And this will provide theoretical and experimental foundation for targeted therapy of leukemia.
