中华眼科杂志
中華眼科雜誌
중화안과잡지
Chinese Journal of Ophthalmology
2010年
6期
494-498
,共5页
青光眼%药物疗法%病人依从%横断面研究
青光眼%藥物療法%病人依從%橫斷麵研究
청광안%약물요법%병인의종%횡단면연구
Glaucoma%Drug therapy%Patient compliance%Cross-sectional studies
目的 研究青光眼患者长期药物治疗的依从性及其影响因素.方法 横断面研究.采用问卷调查与访谈相结合的方式,对门诊长期连续治疗的100例青光眼患者进行调查,了解其药物治疗的依从性及其影响因素.采用SPSS 15.0统计学软件,对影响患者药物治疗依从性的多种因素在X2检验的基础上进行二分类logistic回归分析.结果 100例青光眼患者中,男性54例,女性46例;年龄9～80岁;用药时间从6个月至20年不等.100例中,用药依从者61例(61.0%),不依从者39例(39.0%),总体用药依从性为61.0%.调查分析结果表明,患者性别(X2=0.718)、年龄(X2=0.537)、居住地(X2=0.338)、青光眼类型(X2=3.797)、有无手术史(X2=0.338)及医生处方是否征询患者意见(X2=0.297)、是否向患者交待用药方法(X2=0.157)等因素对药物治疗依从性无明显影响,差异无统计学意义(均P>0.05).二分类logistic回归分析结果表明,患者用药前眼压(P=0.013)、用药种类(P=0.005)、药液是否滴在眼睑皮肤上(P=0.005)、滴眼液时是否需要帮助(P=0.012)、是否定期复查(P=0.011)、自身对青光眼治疗的信心(P=0.004)等因素对药物治疗依从性有显著影响,差异有统计学意义(均P<0.05).患者自述中的药物副作用、滴眼液方案复杂易忘、就医不便(包括候诊时间长)等因素排在影响药物治疗依从性的前3位.结论 临床眼科医师应充分考虑到影响患者药物治疗依从性的多种因素,向患者交代使用抗青光眼药物应注意的问题,给予具体用药指导,以提高青光眼患者的药物治疗依从性,从而增进疗效.
目的 研究青光眼患者長期藥物治療的依從性及其影響因素.方法 橫斷麵研究.採用問捲調查與訪談相結閤的方式,對門診長期連續治療的100例青光眼患者進行調查,瞭解其藥物治療的依從性及其影響因素.採用SPSS 15.0統計學軟件,對影響患者藥物治療依從性的多種因素在X2檢驗的基礎上進行二分類logistic迴歸分析.結果 100例青光眼患者中,男性54例,女性46例;年齡9～80歲;用藥時間從6箇月至20年不等.100例中,用藥依從者61例(61.0%),不依從者39例(39.0%),總體用藥依從性為61.0%.調查分析結果錶明,患者性彆(X2=0.718)、年齡(X2=0.537)、居住地(X2=0.338)、青光眼類型(X2=3.797)、有無手術史(X2=0.338)及醫生處方是否徵詢患者意見(X2=0.297)、是否嚮患者交待用藥方法(X2=0.157)等因素對藥物治療依從性無明顯影響,差異無統計學意義(均P>0.05).二分類logistic迴歸分析結果錶明,患者用藥前眼壓(P=0.013)、用藥種類(P=0.005)、藥液是否滴在眼瞼皮膚上(P=0.005)、滴眼液時是否需要幫助(P=0.012)、是否定期複查(P=0.011)、自身對青光眼治療的信心(P=0.004)等因素對藥物治療依從性有顯著影響,差異有統計學意義(均P<0.05).患者自述中的藥物副作用、滴眼液方案複雜易忘、就醫不便(包括候診時間長)等因素排在影響藥物治療依從性的前3位.結論 臨床眼科醫師應充分攷慮到影響患者藥物治療依從性的多種因素,嚮患者交代使用抗青光眼藥物應註意的問題,給予具體用藥指導,以提高青光眼患者的藥物治療依從性,從而增進療效.
목적 연구청광안환자장기약물치료적의종성급기영향인소.방법 횡단면연구.채용문권조사여방담상결합적방식,대문진장기련속치료적100례청광안환자진행조사,료해기약물치료적의종성급기영향인소.채용SPSS 15.0통계학연건,대영향환자약물치료의종성적다충인소재X2검험적기출상진행이분류logistic회귀분석.결과 100례청광안환자중,남성54례,녀성46례;년령9～80세;용약시간종6개월지20년불등.100례중,용약의종자61례(61.0%),불의종자39례(39.0%),총체용약의종성위61.0%.조사분석결과표명,환자성별(X2=0.718)、년령(X2=0.537)、거주지(X2=0.338)、청광안류형(X2=3.797)、유무수술사(X2=0.338)급의생처방시부정순환자의견(X2=0.297)、시부향환자교대용약방법(X2=0.157)등인소대약물치료의종성무명현영향,차이무통계학의의(균P>0.05).이분류logistic회귀분석결과표명,환자용약전안압(P=0.013)、용약충류(P=0.005)、약액시부적재안검피부상(P=0.005)、적안액시시부수요방조(P=0.012)、시부정기복사(P=0.011)、자신대청광안치료적신심(P=0.004)등인소대약물치료의종성유현저영향,차이유통계학의의(균P<0.05).환자자술중적약물부작용、적안액방안복잡역망、취의불편(포괄후진시간장)등인소배재영향약물치료의종성적전3위.결론 림상안과의사응충분고필도영향환자약물치료의종성적다충인소,향환자교대사용항청광안약물응주의적문제,급여구체용약지도,이제고청광안환자적약물치료의종성,종이증진료효.
Objective To investigate the medication adherence and modulation factors of medication adherence in long-term treated glaucoma patients. Methods It was a cross-sectional study.One hundred glaucoma patients who have been followed-up for more than 6 month in the Second Hospital affiliated to Medical College of Zhejiang University were investigated with questionnaires and interview.The data was analyzed by binary logistic regression and X2 test.Results In the 100 glaucoma patients being ivestigated,the medication compliance of patients is 61(61.0%),the medication non-compliance of patients is 39(39.0%).Age,gender,habitat,glaucoma types,surgical history,inquesting patient before writing out a prescription and informing them the methods for application of eyedrops were not significantly co-related with medication adherence(X2=0.718,0.537,0.338,3.797,0.338,0.297,0.157;P>0.05).Intraocular pressure before treatment,types of eyedrops,instillation of eye-drops to the eyelids,request for help during application of eyedrops,rechecking regularly and confidence in glaucoma treatment were found significantly related to medication adherence(P=0.013,0.005,0.005,0.012,0.011,0.004).However,drug side effect,forgetting application of eyedrops and inconvenience to see a doctor was considered the most important factors by patients in the interview.Conclusions Glaucoma physicians should discuss with patients about the methods for the application of glaucoma medication.This can improve the medication adherence of glaucoma patients and promote the therapeutic effect.
