CAJ | 학술논문

目的探讨2型糖尿病合并血管微血管病变并发症患者血清C反应蛋白(CRP)水平. 方法观察2型糖尿病患者有、无微血管病变并发症和正常对照组的血清CRP水平变化. 结果 2型糖尿病患者有、无微血管病变并发症的血清CRP水平较正常对照组明显增高(P<0.05),而微血管病变组血清CRP比单纯糖尿病(DM)组升高明显(P<0.05);糖尿病患者血清CRP水平与病程、高血压、体重指数、尿白蛋白排泄率、甘油三酯、空腹胰岛素呈正相关(P<0.01). 结论血清CRP增高与2型糖尿病微血管病变发生明显相关,在2型糖尿病微血管病变危险预测中具有重要作用.
목적 탐토2형당뇨병합병혈관미혈관병변병발증환자혈청C반응단백(CRP)수평. 방법 관찰2형당뇨병환자유、무미혈관병변병발증화정상대조조적혈청CRP수평변화. 결과 2형당뇨병환자유、무미혈관병변병발증적혈청CRP수평교정상대조조명현증고(P<0.05),이미혈관병변조혈청CRP비단순당뇨병(DM)조승고명현(P<0.05);당뇨병환자혈청CRP수평여병정、고혈압、체중지수、뇨백단백배설솔、감유삼지、공복이도소정정상관(P<0.01). 결론 혈청CRP증고여2형당뇨병미혈관병변발생명현상관,재2형당뇨병미혈관병변위험예측중구유중요작용.
Objective To explore the serum level of C - reactive protein (CRP) in type 2 diabetes mellitus(T2DM) with mi-crovascular disease. Methods We observed the serum CRP level in T2DM with or without mierovaseular disease and compared with the normal group. Results The serum CRP level were significant higher in T2DM with and without microvaseular disease than the normal group. (P<0.05). CRP was significantly increased in T2DM group as compared with control levels. CRP was significantly increased in T2DM with mierovaseular disease as compared with that in T2DM group(P<0.05). CRP level in dia-betes mellims was positively related with cause of disease,high blood pressure, BMI, UAE, TG, FINS (P<0.05). But there was no relationship between serum CRP and age, FPG,TC (P>0.05). Conclusion Increase in CRP is closely correlate with microvaseular disease in T2DM, suggesting that CRP plays an importan role in risk prediction of the T2DM patients with mierovas-cular disease.