遗传学报
遺傳學報
유전학보
ACTA GENETICA SINICA
2006年
12期
1060-1072
,共13页
陈晶%李辉%覃振东%刘文泓%林伟雄%尹瑞兴%金力%潘尚领
陳晶%李輝%覃振東%劉文泓%林偉雄%尹瑞興%金力%潘尚領
진정%리휘%담진동%류문홍%림위웅%윤서흥%금력%반상령
Y-染色体%壮族%内部遗传结构
Y-染色體%壯族%內部遺傳結構
Y-염색체%장족%내부유전결구
Y chromosome%Zhuang%internal genetic structure
壮族是中国最大的少数民族,与东南亚的泰老族群关系密切,在东亚人群的遗传结构研究中地位非常特殊.本研究调查了壮族各个支系的Y染色体多样性,通过主成分分析、聚类分析和分子方差分析,揭示壮族的内部父系遗传结构.结果发现,壮族的主要Y染色体单倍群为O*,O2a,O1.传统的对壮族按方言分为南北二组的分类方法在遗传上并没有依据,壮族支系体现出从东往西的梯度变化过程.这说明壮族的结构中有几个层次,最早的成分普遍出现在各个支系中,第二层是由东部来的百越核心成分,第三层是北方来的汉族成分.壮族内部遗传结构的分析将有助于对东亚人群的南来起源的研究.
壯族是中國最大的少數民族,與東南亞的泰老族群關繫密切,在東亞人群的遺傳結構研究中地位非常特殊.本研究調查瞭壯族各箇支繫的Y染色體多樣性,通過主成分分析、聚類分析和分子方差分析,揭示壯族的內部父繫遺傳結構.結果髮現,壯族的主要Y染色體單倍群為O*,O2a,O1.傳統的對壯族按方言分為南北二組的分類方法在遺傳上併沒有依據,壯族支繫體現齣從東往西的梯度變化過程.這說明壯族的結構中有幾箇層次,最早的成分普遍齣現在各箇支繫中,第二層是由東部來的百越覈心成分,第三層是北方來的漢族成分.壯族內部遺傳結構的分析將有助于對東亞人群的南來起源的研究.
장족시중국최대적소수민족,여동남아적태로족군관계밀절,재동아인군적유전결구연구중지위비상특수.본연구조사료장족각개지계적Y염색체다양성,통과주성분분석、취류분석화분자방차분석,게시장족적내부부계유전결구.결과발현,장족적주요Y염색체단배군위O*,O2a,O1.전통적대장족안방언분위남북이조적분류방법재유전상병몰유의거,장족지계체현출종동왕서적제도변화과정.저설명장족적결구중유궤개층차,최조적성분보편출현재각개지계중,제이층시유동부래적백월핵심성분,제삼층시북방래적한족성분.장족내부유전결구적분석장유조우대동아인군적남래기원적연구.
Zhuang, the largest ethnic minority population in China, is one of the descendant groups of the ancient Bai-Yue.Linguistically, Zhuang languages are grouped into northern and southern dialects. To characterize its genetic structure, 13 East Asian-specific Y-chromosome biallelic markers and 7 Y-chromosome short tandem repeat (STR) markers were used to infer the haplogroups of Zhuang populations. Our results showed that O*, O2a, and O1 are the predominant haplogroups in Zhuang.Frequency distribution and principal component analysis showed that Zhuang was closely related to groups of Bai-Yue origin and therefore was likely to be the descendant of Bai-Yue. The results of principal component analysis and hierarchical clustering analysis contradicted the linguistically derived north-south division. Interestingly, a west-east clinal trend of haplotype frequency changes was observed, which was supported by AMOVA analysis that showed that between-population variance of east-west division was larger than that of north-south division. O* network suggested that the Hongshuihe branch was the center of Zhuang.Our study suggests that there are three major components in Zhuang. The O* and O2a constituted the original component; later, O1was brought into Zhuang, especially eastern Zhuang; and fmally, northern Han population brought O3 into the Zhuang populations.