国际泌尿系统杂志
國際泌尿繫統雜誌
국제비뇨계통잡지
INTERNATIONAL JOURNAL OF UROLOGY AND NEPHROLOGY
2012年
5期
605-606,619
,共3页
肾移植%移植物排斥%蛋白尿%血压%肌酸酐
腎移植%移植物排斥%蛋白尿%血壓%肌痠酐
신이식%이식물배척%단백뇨%혈압%기산항
Kidney Transplantation%Graft Rejection%Albuminuria%Blood Pressure%Creatinine
目的 探讨移植肾慢性排斥反应患者治疗前后24h尿蛋白定量、血肌酐及血压水平变化情况.方法 选取行肾移植术后发生移植肾慢性排斥反应的70例患者为实验组,并选取同期行肾移植术后不伴移植肾慢性排斥反应的正常患者70例为对照组.对于发生排斥反应的患者给予冲击治疗和调整免疫抑制剂的剂量逆转排斥反应.将两组患者行肾移植术后的和出院前的24h尿蛋白定量、血肌酐及血压进行研究比较.结果 经研究发现,治疗前实验组的24h尿蛋白定量、血肌酐及血压水平明显高于对照组,治疗后降低为基本正常,有显著性差异或有非常显著性差异(P＜0.01).结论 移植肾慢性排斥患者的24h尿蛋白定量、血肌酐及血压水平变化呈现一定的规律性,抗排斥反应治疗可大大改善其水平.研究证明24h尿蛋白定量、血肌酐及血压水平对移植肾慢性排斥反应的临床诊断和治疗具有重要价值.
目的 探討移植腎慢性排斥反應患者治療前後24h尿蛋白定量、血肌酐及血壓水平變化情況.方法 選取行腎移植術後髮生移植腎慢性排斥反應的70例患者為實驗組,併選取同期行腎移植術後不伴移植腎慢性排斥反應的正常患者70例為對照組.對于髮生排斥反應的患者給予遲擊治療和調整免疫抑製劑的劑量逆轉排斥反應.將兩組患者行腎移植術後的和齣院前的24h尿蛋白定量、血肌酐及血壓進行研究比較.結果 經研究髮現,治療前實驗組的24h尿蛋白定量、血肌酐及血壓水平明顯高于對照組,治療後降低為基本正常,有顯著性差異或有非常顯著性差異(P＜0.01).結論 移植腎慢性排斥患者的24h尿蛋白定量、血肌酐及血壓水平變化呈現一定的規律性,抗排斥反應治療可大大改善其水平.研究證明24h尿蛋白定量、血肌酐及血壓水平對移植腎慢性排斥反應的臨床診斷和治療具有重要價值.
목적 탐토이식신만성배척반응환자치료전후24h뇨단백정량、혈기항급혈압수평변화정황.방법 선취행신이식술후발생이식신만성배척반응적70례환자위실험조,병선취동기행신이식술후불반이식신만성배척반응적정상환자70례위대조조.대우발생배척반응적환자급여충격치료화조정면역억제제적제량역전배척반응.장량조환자행신이식술후적화출원전적24h뇨단백정량、혈기항급혈압진행연구비교.결과 경연구발현,치료전실험조적24h뇨단백정량、혈기항급혈압수평명현고우대조조,치료후강저위기본정상,유현저성차이혹유비상현저성차이(P＜0.01).결론 이식신만성배척환자적24h뇨단백정량、혈기항급혈압수평변화정현일정적규률성,항배척반응치료가대대개선기수평.연구증명24h뇨단백정량、혈기항급혈압수평대이식신만성배척반응적림상진단화치료구유중요개치.
Objectives To investigate the change before and after treatment of 24h urinary protein 、SCr and BP in chronic rejection of kidney transplant patients.Methods 70 kidney transplant patients in chronic rejection treated with anti-rejection were selected as observation group,and 70 kidney transplant patients without chronic rejection as control group,then the 24h urinary protein,SCr and BP of the two groups before and after the treatment were studied and compared.Results The 24h urinary protein,SCr and BP of the observation group before the treatment were higher than those of control group,and the levels after the treatment at 24 hours declined,and almost equal to those of control group( P ＜ 0.01 ).There were significant or very significant differences.Conclusions The change of the 24h urinary protein,SCr and BP in the kidney transplant patients in chronic rejection treated with anti-rejection is regular,chronic rejection combined with the treatment of anti-rejection should decrease the levels.
