中国临床实用医学
中國臨床實用醫學
중국림상실용의학
CHINA CLINICAL PRACTICAL MEDICINE
2009年
2期
42-43
,共2页
唐馨芬%赵中华%林同顺%刘艳
唐馨芬%趙中華%林同順%劉豔
당형분%조중화%림동순%류염
血清D-二聚体%健康人群%免疫透射比浊法
血清D-二聚體%健康人群%免疫透射比濁法
혈청D-이취체%건강인군%면역투사비탁법
Serum D-dimer%Normal population%Turbidimetric immunoassay
目的 对表面健康人群的血清D-二聚体水平和分布作初步探讨.方法 用免疫透射比浊法在日立7020全自动生化分析仪上检测.结果 测定338例表面健康人群血清D-二聚体水平,=1.37mg/L,95%的参考范围0.1～2.64 mg/L,呈正态分布;其中男165例,=1.28 mg/L,95%的参考范围0.15～2.41 mg/L;女173例,=1.46 mg/L,95%的参考范围0.04～2.88 mg/L;男女血清D-二聚体水平比较,P<0.05,差异有统计学意义;17～30岁年龄段血清D-二聚体水平=1.33 mg/L;31～65岁年龄段血清D-二聚体水平=1.40 mg/L,两年龄段血清D-二聚体水平比较,P>0.05,差异无统计学意义;血清与肝素抗凝血浆D-二聚体结果比较,P<0.01,差异有统计学意义,直线回归与相关分析显示:Y=1.0689X+1.464,r=0.9967;用日本血清管与国产血清管比较,P<0.01,差异有统计学意义.结论 通过对国内338例表面健康人群血清D-二聚体浓度的测定和分析,初步界定国内人群血清D-二聚体浓度95%的参考范围为0.1～2.64 mg/L,呈正态分布;血清与肝素抗凝血浆D-二聚体的参考范围不能共用,但相关性良好.
目的 對錶麵健康人群的血清D-二聚體水平和分佈作初步探討.方法 用免疫透射比濁法在日立7020全自動生化分析儀上檢測.結果 測定338例錶麵健康人群血清D-二聚體水平,=1.37mg/L,95%的參攷範圍0.1～2.64 mg/L,呈正態分佈;其中男165例,=1.28 mg/L,95%的參攷範圍0.15～2.41 mg/L;女173例,=1.46 mg/L,95%的參攷範圍0.04～2.88 mg/L;男女血清D-二聚體水平比較,P<0.05,差異有統計學意義;17～30歲年齡段血清D-二聚體水平=1.33 mg/L;31～65歲年齡段血清D-二聚體水平=1.40 mg/L,兩年齡段血清D-二聚體水平比較,P>0.05,差異無統計學意義;血清與肝素抗凝血漿D-二聚體結果比較,P<0.01,差異有統計學意義,直線迴歸與相關分析顯示:Y=1.0689X+1.464,r=0.9967;用日本血清管與國產血清管比較,P<0.01,差異有統計學意義.結論 通過對國內338例錶麵健康人群血清D-二聚體濃度的測定和分析,初步界定國內人群血清D-二聚體濃度95%的參攷範圍為0.1～2.64 mg/L,呈正態分佈;血清與肝素抗凝血漿D-二聚體的參攷範圍不能共用,但相關性良好.
목적 대표면건강인군적혈청D-이취체수평화분포작초보탐토.방법 용면역투사비탁법재일립7020전자동생화분석의상검측.결과 측정338례표면건강인군혈청D-이취체수평,=1.37mg/L,95%적삼고범위0.1～2.64 mg/L,정정태분포;기중남165례,=1.28 mg/L,95%적삼고범위0.15～2.41 mg/L;녀173례,=1.46 mg/L,95%적삼고범위0.04～2.88 mg/L;남녀혈청D-이취체수평비교,P<0.05,차이유통계학의의;17～30세년령단혈청D-이취체수평=1.33 mg/L;31～65세년령단혈청D-이취체수평=1.40 mg/L,량년령단혈청D-이취체수평비교,P>0.05,차이무통계학의의;혈청여간소항응혈장D-이취체결과비교,P<0.01,차이유통계학의의,직선회귀여상관분석현시:Y=1.0689X+1.464,r=0.9967;용일본혈청관여국산혈청관비교,P<0.01,차이유통계학의의.결론 통과대국내338례표면건강인군혈청D-이취체농도적측정화분석,초보계정국내인군혈청D-이취체농도95%적삼고범위위0.1～2.64 mg/L,정정태분포;혈청여간소항응혈장D-이취체적삼고범위불능공용,단상관성량호.
Objective To make the preliminary discussion of the serum D-dimer level in Normal popu-lation. Methods Serum D-dimer was detected by turbidimetric immunoassay on the Hitachi 7020 automatic bi-ochemistry analyzer. Results 338 apparently healthy controls were examined. The average value was 1.37 mg/ L,95% reference range 0. 1 ～ 2. 64 mg/L, assumes the normal distribution, male 165 examples, average value 1.28 mg/L,95% reference range 0. 15 ～2.41 mg/L; Female 173 examples,average value 1.46 mg/L,95% ref-erence scope 0. 04 ～ 2. 88 mg/L; In the healths controls, there was significantly deference of serum -dimer lev-el between the male and the female(P < 0. 05) , there was no significantly deference of serum D-dimer level in the age groups of 17～30 year old and 31～65 year old(P >0. 05) ; Compares with serum and heparin plasma, or the serum tube made by different country(Japan and China) , the difference has the extremely remarkable sta-tistics significance(P < 0. 001). Conclusion Preliminary defined the 95% reference value of serum D-dimer concentration was 0.1 ～2.64 mg/L; The serum and the heparin plasma D-dimer reference scope cannot use in common, but the relevance is good.
