CAJ | 학술논문

目的探讨磁共振氰质子波谱成像(~1H-MRSI)在胶质母细胞瘤诊断中的应用价值.方法经手术病理证实的29例胶质母细胞瘤,术前均行常规MRI及~1H-MRSI检查,根据常规MRI及~1H-MRSI特点预测其病理性质.并总结出本组病例~1H-MRSI特点.结果 29例中,术前预测正确25例,典型的胶质母细胞瘤的~1H-MRSI表现为NAA明显降低,Cho升高,肿瘤内或边缘Cr/NAA比率显著升高,出现Lac峰.结论肿瘤内或边缘Cr/NAA比率显著升高是胶质母细胞瘤的主要特征,术前~1H-MRSI能为胶质母细胞瘤的诊断提供较高的诊断价值.
목적 탐토자공진청질자파보성상(~1H-MRSI)재효질모세포류진단중적응용개치.방법 경수술병리증실적29례효질모세포류,술전균행상규MRI급~1H-MRSI검사,근거상규MRI급~1H-MRSI특점예측기병이성질.병총결출본조병례~1H-MRSI특점.결과 29례중,술전예측정학25례,전형적효질모세포류적~1H-MRSI표현위NAA명현강저,Cho승고,종류내혹변연Cr/NAA비솔현저승고,출현Lac봉.결론 종류내혹변연Cr/NAA비솔현저승고시효질모세포류적주요특정,술전~1H-MRSI능위효질모세포류적진단제공교고적진단개치.
Objective To study the value of ~1H-MRSI in the diagnosis of cerebral glioblastoma.Methods 29 patients with cerebral glioblastoma confirmed by postoperative pathology were examined with routine MRI and ~1H-MILSI before operation.The preoperative pathological diagnosis was presumed according to the MRI and ~1H-MRSI for each patient.The characteristics of ~1H-MRSI in glioblastoma were concluded.Results The preoperative right presumption of diagnosis was achieved in 25 patients.The typical ~1H-MRSI features of cerebral glioblastoma included:evident decrease of NAA,increase of Cho,significant increase of the Cr/NAA ratio within or at the edge of tumors.and the appearance of Lac.Conclusion Significant ilrlcreage of the Cr/NAA ratio within or at the edge of tumors is the main characteristic of ~1H-MRSI in cerebral glioblastom Preoperative ~1H-MRSI is of certain value in the diagnosis of cerebral glioblastoma.