天然产物研究与开发
天然產物研究與開髮
천연산물연구여개발
NATURAL PRODUCT RESEARCH AND DEVELOPMENT
2011年
1期
10-14,42
,共6页
李苏梅%田新朋%牛四文%张文军%张偲%鞠建华%张长生
李囌梅%田新朋%牛四文%張文軍%張偲%鞠建華%張長生
리소매%전신붕%우사문%장문군%장시%국건화%장장생
南海沉积环境%海洋放线菌%海洋微生物天然产物%链霉菌%抗霉素
南海沉積環境%海洋放線菌%海洋微生物天然產物%鏈黴菌%抗黴素
남해침적배경%해양방선균%해양미생물천연산물%련매균%항매소
marine sediments of South China Sea%marine actinomycetes%marine microbial natural products%Streptomyces%antimycins
我们从南海海底沉积环境分离了一株放线菌SCSIO 1635,经16S rDNA的序列分析将该株菌鉴定为链霉菌属.我们从该菌的发酵液中分离得到了4个化合物,经质谱和核磁共振波谱解析,确定为抗霉素类化合物:异构体 antimycin A1a和A1b(1)、deisovalerylblastmycin(2)、kitamycin A(3)和antimycin A9(4).
我們從南海海底沉積環境分離瞭一株放線菌SCSIO 1635,經16S rDNA的序列分析將該株菌鑒定為鏈黴菌屬.我們從該菌的髮酵液中分離得到瞭4箇化閤物,經質譜和覈磁共振波譜解析,確定為抗黴素類化閤物:異構體 antimycin A1a和A1b(1)、deisovalerylblastmycin(2)、kitamycin A(3)和antimycin A9(4).
아문종남해해저침적배경분리료일주방선균SCSIO 1635,경16S rDNA적서렬분석장해주균감정위련매균속.아문종해균적발효액중분리득도료4개화합물,경질보화핵자공진파보해석,학정위항매소류화합물:이구체 antimycin A1a화A1b(1)、deisovalerylblastmycin(2)、kitamycin A(3)화antimycin A9(4).
The strain SCSIO 1635 was isolated from marine sediment of the South China Sea,and identified as a member of Streptomyces according to the 16S rDNA sequence.Four compounds were isolated from Streptomyces sp.SCSIO 1635.The compounds were found to be structurally-related to antimycins by detailed analyses of MS and NMR spectroscopic data,and were identified as antimycin A1a and A1b(1),deisovalerylblastmycin (2),kitamycin A (3),and antimycin A9(4),respectively.
