CAJ | 학술논문

目的探讨额叶和颞叶癫痫患者的执行功能障碍状况.方法选择癫痫患者55例,其中额叶癫痫组25例,颞叶癫痫组30例,对照组50例,其性别、年龄、受教育程度相匹配,采用简明精神状况量表(MMSE)测评患者的定向力、记忆力、注意力和计算力、回忆能力以及语言能力,并利用Stroop色词测验和连线测验测评患者的执行功能.结果额叶、颞叶癫痫患者的MMSE总评分别是[(26.02±0.30)分]和[(25.82±0.67)分],与正常对照组比较,差异有统计学意义(P＜0.05).在Stroop色词测验中,额叶、颞叶癫痫组卡片B和卡片C的正确数、3张卡片的耗时数、SIE与正常对照组比较,均差异有统计学意义(P＜0.05),两患者组间差异有统计学意义(P＜0.05).在连线测验中,额叶、颢叶癫痫组TMTA、TMTB及( TMTB-TMTA)与正常对照组比较,差异有统计学意义(p＜0.05),两患者组间差异有统计学意义(P＜0.05).结论额叶和颞叶癫痫患者存在执行功能障碍,而额叶癫痫患者执行功能障碍较明显.
목적 탐토액협화섭협전간환자적집행공능장애상황.방법 선택전간환자55례,기중액협전간조25례,섭협전간조30례,대조조50례,기성별、년령、수교육정도상필배,채용간명정신상황량표(MMSE)측평환자적정향력、기억력、주의력화계산력、회억능력이급어언능력,병이용Stroop색사측험화련선측험측평환자적집행공능.결과 액협、섭협전간환자적MMSE총평분별시[(26.02±0.30)분]화[(25.82±0.67)분],여정상대조조비교,차이유통계학의의(P＜0.05).재Stroop색사측험중,액협、섭협전간조잡편B화잡편C적정학수、3장잡편적모시수、SIE여정상대조조비교,균차이유통계학의의(P＜0.05),량환자조간차이유통계학의의(P＜0.05).재련선측험중,액협、호협전간조TMTA、TMTB급( TMTB-TMTA)여정상대조조비교,차이유통계학의의(p＜0.05),량환자조간차이유통계학의의(P＜0.05).결론 액협화섭협전간환자존재집행공능장애,이액협전간환자집행공능장애교명현.
Objective To investigate the executive functions of the frontal and temporal lobe epilepsy patients.Methods Fifty-five epilepsy patients (twenty-five frontal lobe epilepsy patients and thirty temporal lobe epilepsy patients) and fifty age,gender and education matched healthy controls were evaluated by means of Mini Mental State Examination ( MMSE ).Executive function was assessed using Stroop color words test and trail making test.Results MMSE total score of frontal and temporal lobe epilepsy patients were ( 26.02 ± 0.30) and (25.82 ± 0.67 ),respectively.There was significant abnormality between epilepsy patients and the controls (P ＜0.05).Compared with normal control group,FLP group and TLP group took longer time and their score was lower in stroop color words test (P＜0.05).There were significant difference between FLP and TLP on card B and C's reading time,correct number and strcop interference effects (P＜0.05).The epilepsy patients performed significantly worse than the controls in whole trail making test (P＜0.05).The scores indicate that the TLE group outperformed the FLE group on all analysis values (P ＜ 0.05 ).Conclusion The frontal and temporal lobe epilepsy patients have executive function deficit.The FLE group has prominent deficits in executive functioning.