CAJ | 학술논문

报告1例硬化性黏液水肿患者使用沙利度胺治疗后疗效显著.患者男,47岁.全身出现丘疹2年余,皮肤变硬半年.经治疗症状改善不明显,皮肤增厚、变硬,范围逐渐扩大,全身皮肤呈黑褐色.固定电泳检测发现单克隆IgG-λ.经皮损组织病理检查诊断为硬化性黏液水肿.给予沙利度胺50mg,每日 3次口服.3个月后随访,患者皮肤明显变薄、变软,肤色变浅.
보고1례경화성점액수종환자사용사리도알치료후료효현저.환자남,47세.전신출현구진2년여,피부변경반년.경치료증상개선불명현,피부증후、변경,범위축점확대,전신피부정흑갈색.고정전영검측발현단극륭IgG-λ.경피손조직병리검사진단위경화성점액수종.급여사리도알50mg,매일 3차구복.3개월후수방,환자피부명현변박、변연,부색변천.
This article reports a case of scleromyxedema with significant effect by thalidomide treatment. A 47-year-oldmale patient presented general firm papules for 2 years and hardening lesion for 6 months. After using acitretin 10 mg/d for6 months, the skin was getting thicker and harder than before, and the lesion range expanded. Immunofixation electrophoresisfound monoclone IgG-λ. He was diagnosed as scleromyxedema by pathological examination. After given oral thalidminde 50mg tid for 3 months, the skin became progressively softer, thinner and lighter.