CAJ | 학술논문

为冻干甲型肝炎（甲肝）减毒活疫苗的生产、贮存、使用等提供科学依据，对甲肝病毒L－A－1疫苗株制备的连续多批冻干甲肝减毒活疫苗，在放置不同温度、不同时间后的稳定性进行了研究。结果表明：疫苗置－20℃　28个月、2℃～8℃　20个月、25℃　4个月、37℃　14天，其病毒滴度仍达到≥6.5LogCCID50／ml的合格滴度，表明此疫苗稳定性良好。
위동간갑형간염（갑간）감독활역묘적생산、저존、사용등제공과학의거，대갑간병독L－A－1역묘주제비적련속다비동간갑간감독활역묘，재방치불동온도、불동시간후적은정성진행료연구。결과표명：역묘치－20℃　28개월、2℃～8℃　20개월、25℃　4개월、37℃　14천，기병독적도잉체도≥6.5LogCCID50／ml적합격적도，표명차역묘은정성량호。
The stability of freeze-dry live attenuated hepatitis A vaccine prepared with L-A-1 strain was studied. The titer of the vaccine still reached ≥6.5Log CCID50/ml after having been stored at -20℃ for 28 months, 2℃-8℃ for 20 months, 25℃ for 4 months and 37℃ for 14 days. This demonstrated that the stability of the vaccine is satisfactory.