CAJ | 학술논문

目的探讨腮腺手术中以不同方式植入脱细胞异体真皮基质的中长期变化.方法 20只新西兰大白兔随机分为3月、6月、9月、12月组(每组5只),建立腮腺手术中将脱细胞异体真皮基质以正、反两种方向植入的模型.对模型进行临床和病理观察.结果 ①新生血管在脱细胞异体真皮基质中呈单向性生长.腮腺术中反向植入补片时,脱细胞异体真皮基质与面神经之间瘢痕粘连不紧密,易于分离.②脱细胞异体真皮基质愈合时,血管、神经纤维都可长入,并最终布满全层.结论 ①腮腺手术中反向植入脱细胞异体真皮基质,因其与面神经之间瘢痕粘连不紧密且易于分离,这将有利于防止二次手术时损伤面神经.②在本研究中,脱细胞异体真皮基质不能阻止神经纤维的长入.所以其预防Frey's综合征的持久性有待进一步观察.
목적 탐토시선수술중이불동방식식입탈세포이체진피기질적중장기변화.방법 20지신서란대백토수궤분위3월、6월、9월、12월조(매조5지),건립시선수술중장탈세포이체진피기질이정、반량충방향식입적모형.대모형진행림상화병리관찰.결과 ①신생혈관재탈세포이체진피기질중정단향성생장.시선술중반향식입보편시,탈세포이체진피기질여면신경지간반흔점련불긴밀,역우분리.②탈세포이체진피기질유합시,혈관、신경섬유도가장입,병최종포만전층.결론 ①시선수술중반향식입탈세포이체진피기질,인기여면신경지간반흔점련불긴밀차역우분리,저장유리우방지이차수술시손상면신경.②재본연구중,탈세포이체진피기질불능조지신경섬유적장입.소이기예방Frey's종합정적지구성유대진일보관찰.
Objective To investigate the long-time changes of acellular dermal matrix (ADM) implanted into the surgical field after parotidectomy in different ways.Methods Twenty New Zealand white rabbits were used as animal model and randomly divided into 4 groups (n = 5). Parotid gland surgery was established and ADM film was implanted in all the four groups. Animals were sacrificed every 3 months after surgery for pathological observation.Results The rough side of ADM film can be attached and combined with tissues well, while the smooth side of which can not be attached.Conclusion Since ADM can be combined with nerve fibers, the long-term prevention from Frey's syndrome by surgical implantation of ADM in parotid gland might be limited. However, this study also indicated that reverse implantation of the ADM film can be conducive to parotid second surgery, for it can possibly prevent facial nerve injury.