CAJ | 학술논문

目的：探讨宫颈环形电切术（LEEP）及微波治疗Ⅲ°宫颈糜烂的临床效果。方法：选择Ⅲ°宫颈糜烂患者120例,随机将其分为两组,治疗组采用LEEP治疗;对照组采用传统的微波治疗,每组各60例。评定两组患者术中出血量、术后15 d脱痂止血及治疗后60 d治愈、好转和无效情况,治疗后90 dHPV高危型持续感染率。结果：LEEP60例（其中HPV感染20例）,术后15 d脱痂止血2例,术后60、90 d复查,60例宫颈创面100%愈合（愈合率100%）;术后90 d复查HPV高危型持续感染2例（10%）,对照组60例（其中HPV感染18例）,术后15 d脱痂止血12例,术后60 d复查,宫颈创面完全愈合42人（愈合率70%）,18例创面愈合1/3~1/2,4例完全未愈合;术后90 d复查,HPV高危型持续感染6例（30%）。两组比较差异具有统计学意义（P〈0.05）。结论：LEEP治疗宫颈Ⅲ°糜烂,具有创面愈合时间短,HPV持续感染率低的优点,其疗效优于传统微波治疗。故重度宫颈糜烂可首选LEEP治疗。
목적：탐토궁경배형전절술（LEEP）급미파치료Ⅲ°궁경미란적림상효과。방법：선택Ⅲ°궁경미란환자120례,수궤장기분위량조,치료조채용LEEP치료;대조조채용전통적미파치료,매조각60례。평정량조환자술중출혈량、술후15 d탈가지혈급치료후60 d치유、호전화무효정황,치료후90 dHPV고위형지속감염솔。결과：LEEP60례（기중HPV감염20례）,술후15 d탈가지혈2례,술후60、90 d복사,60례궁경창면100%유합（유합솔100%）;술후90 d복사HPV고위형지속감염2례（10%）,대조조60례（기중HPV감염18례）,술후15 d탈가지혈12례,술후60 d복사,궁경창면완전유합42인（유합솔70%）,18례창면유합1/3~1/2,4례완전미유합;술후90 d복사,HPV고위형지속감염6례（30%）。량조비교차이구유통계학의의（P〈0.05）。결론：LEEP치료궁경Ⅲ°미란,구유창면유합시간단,HPV지속감염솔저적우점,기료효우우전통미파치료。고중도궁경미란가수선LEEP치료。
Objective： To investigate the clinical results of cervical LEEP（loop electrosurgical excisional procedure） and microwave therapy in treatment of class III cervical erosion.Methods： One hundred and twenty patients with class III cervical erosion were randomly divided into treatment group（LEEP therapy） and control group（traditional microwave therapy）,with 60 cases in each group.Blood loss,effects on exuvial hemorrhage at 15 days and 60 days postoperative,as well as the rate of high-risk HPV infection at 90days postoperative were evaluated.Results： There were 20 cases of HPV infection in LEEP group,2 cases of exuvial hemorrhage were observed at 15 d postoperative,all cases of cervical wounds were 100% healed at 60 d and 90 d postoperative（healing rate 100%）;2 cases（10%） showed high-risk HPV persistent infection at 90 d postoperative.There were 18 cases of HPV infection in control group,12 cases of exuvial hemorrhage were observed at 15 d postoperative,42 cases of cervical wounds were 100% healed at 60 d and 90 d postoperative（healing rate 70%）,meanwhile in 18 cases,about 1/3 to 1/2 of wound healed,and 4 patients did not heal at all;6 cases（30%） showed high-risk HPV persistent infection at 90 d postoperative.The data showed that there were statistic significance between the two groups in healing effect and infection rate（P0.05）.Conclusion： Compared to the microwave therapy,LEEP therapy got better curative effect with shorter healing time and lower HPV persistent infection rates in treatment of class III cervical erosion.