中华消化外科杂志
中華消化外科雜誌
중화소화외과잡지
CHINESE JOURNAL OF DIGESTIVE SURGERY
2012年
4期
343-345
,共3页
胰腺肿瘤,囊性%恶性肿瘤%危险因素
胰腺腫瘤,囊性%噁性腫瘤%危險因素
이선종류,낭성%악성종류%위험인소
Pancreatic neoplasms,cystic%Malignant tumors%Risk factors
目的 探讨恶性胰腺囊性肿瘤的临床相关因素.方法 回顾性分析2000年5月至2011年5月天津医科大学总医院收治的45例经手术治疗的胰腺囊性肿瘤患者的临床资料,根据病理检查结果分为良性肿瘤+癌前病变组(35例)和恶性肿瘤组(10例),分析胰腺囊性肿瘤的临床症状和影像学特征,以及与恶性胰腺囊性肿瘤的相关性.单因素分析采用x2检验,多因素分析采用Logistic回归模型.结果 本组中51％ (23/45)的患者有临床症状,包括腹痛、黄疸、消瘦、恶心呕吐等,49％(22/45)的患者无临床症状,为其他原因就诊时发现.良性胰腺囊肿在影像学检查中的特征为胰腺钙化和分隔;恶性胰腺囊性肿瘤的特征为肿瘤结节、淋巴结肿大、胆管扩张、胰管扩张等.单因素分析结果显示:患者年龄、有无临床症状、黄疸、消瘦、胰管扩张与恶性肿瘤密切相关(x2=4.220,4.294,4.645,7.705,4.645,P＜0.05);多因素分析结果显示:年龄≥60岁、胰管扩张和有临床症状与恶性肿瘤具有显著的相关性,其相关性依次逐渐增高( OR=1.573,2.674,2.723,P＜0.05).结论 年龄≥60岁、胰管扩张和有临床症状是恶性胰腺囊性肿瘤的危险因素.
目的 探討噁性胰腺囊性腫瘤的臨床相關因素.方法 迴顧性分析2000年5月至2011年5月天津醫科大學總醫院收治的45例經手術治療的胰腺囊性腫瘤患者的臨床資料,根據病理檢查結果分為良性腫瘤+癌前病變組(35例)和噁性腫瘤組(10例),分析胰腺囊性腫瘤的臨床癥狀和影像學特徵,以及與噁性胰腺囊性腫瘤的相關性.單因素分析採用x2檢驗,多因素分析採用Logistic迴歸模型.結果 本組中51％ (23/45)的患者有臨床癥狀,包括腹痛、黃疸、消瘦、噁心嘔吐等,49％(22/45)的患者無臨床癥狀,為其他原因就診時髮現.良性胰腺囊腫在影像學檢查中的特徵為胰腺鈣化和分隔;噁性胰腺囊性腫瘤的特徵為腫瘤結節、淋巴結腫大、膽管擴張、胰管擴張等.單因素分析結果顯示:患者年齡、有無臨床癥狀、黃疸、消瘦、胰管擴張與噁性腫瘤密切相關(x2=4.220,4.294,4.645,7.705,4.645,P＜0.05);多因素分析結果顯示:年齡≥60歲、胰管擴張和有臨床癥狀與噁性腫瘤具有顯著的相關性,其相關性依次逐漸增高( OR=1.573,2.674,2.723,P＜0.05).結論 年齡≥60歲、胰管擴張和有臨床癥狀是噁性胰腺囊性腫瘤的危險因素.
목적 탐토악성이선낭성종류적림상상관인소.방법 회고성분석2000년5월지2011년5월천진의과대학총의원수치적45례경수술치료적이선낭성종류환자적림상자료,근거병리검사결과분위량성종류+암전병변조(35례)화악성종류조(10례),분석이선낭성종류적림상증상화영상학특정,이급여악성이선낭성종류적상관성.단인소분석채용x2검험,다인소분석채용Logistic회귀모형.결과 본조중51％ (23/45)적환자유림상증상,포괄복통、황달、소수、악심구토등,49％(22/45)적환자무림상증상,위기타원인취진시발현.량성이선낭종재영상학검사중적특정위이선개화화분격;악성이선낭성종류적특정위종류결절、림파결종대、담관확장、이관확장등.단인소분석결과현시:환자년령、유무림상증상、황달、소수、이관확장여악성종류밀절상관(x2=4.220,4.294,4.645,7.705,4.645,P＜0.05);다인소분석결과현시:년령≥60세、이관확장화유림상증상여악성종류구유현저적상관성,기상관성의차축점증고( OR=1.573,2.674,2.723,P＜0.05).결론 년령≥60세、이관확장화유림상증상시악성이선낭성종류적위험인소.
Objective To investigate the clinical correlative factors of malignant cystic pancreatic tumors.Methods The clinical data of 45 patients who received cystic pancreatic tumor resection at the General Hospital of Tianjin Medical University from May 2000 to May 2011 were retrospectively analyzed.All patients were divided into benign tumors + precancerous lesions group (35 patients) and malignant tumor group (10 patients).The clinical symptoms and imaging features of cystic pancreatic tumors were analyzed.All data were analyzed by chisquare test or Logistic regression analysis.Results Abdominal pain,jaundice,emaciation,nausea and vomiting were observed in 23 patients (51％),and 22 (49％) patients had no clinical symptoms.The clinical features of benign pancreatic cyst included pancreatic calcification and pancreatic divisum,while the clinical features of malignant pancreatic cystic tumors were nodules,swelling of lymph nodes,dilation of biliary and pancreatic duct.The results of univariate analysis showed that age ≥ 60 years,presence of symptoms,jaundice,emaciation,dilation of pancreatic duct were the correlative factors of malignant cystic pancreatic tumors ( x2 =4.220,4.294,4.645,7.705,4.645,P ＜ 0.05 ).The results of multiple logistic regression analysis found that age ≥60 years,dilation of pancreatic duct and presence of clinical symptoms were the correlative factors of malignant cystic pancreatic tumors ( OR =1.573,2.674,2.723,P ＜ 0.05).Conclusion Age≥60 years,dilation of pancreatic duct and presence of clinical symptoms are the correlative factors of malignant cystic pancreatic tumors.
