CAJ | 학술논문

本文对182例婴儿肝炎综合征患儿进行巨细胞病毒(CMV)检查,结果病毒分离及/或血清学阳性共92例,阳性率为50.55%.实验证明GMV在肝炎综合征的各种病原中占首位.除尿标本以外,少数患儿可从唾液及母乳中分离出来.反复检查证明有长期间歇排毒现象.本文从胆道闭锁婴儿的肝活组织及尸检肝组织中分离到CMV,从病毒学证明胆道闭锁的炎症学说,说明CMV.肝炎可能发展为胆道闭锁.从一例胆总管囊肿患儿的肝活组织亦分离到CNIV,说明CMV肝炎与胆总管囊肿亦有密切关系.
본문대182례영인간염종합정환인진행거세포병독(CMV)검사,결과병독분리급/혹혈청학양성공92례,양성솔위50.55%.실험증명GMV재간염종합정적각충병원중점수위.제뇨표본이외,소수환인가종타액급모유중분리출래.반복검사증명유장기간헐배독현상.본문종담도폐쇄영인적간활조직급시검간조직중분리도CMV,종병독학증명담도폐쇄적염증학설,설명CMV.간염가능발전위담도폐쇄.종일례담총관낭종환인적간활조직역분리도CNIV,설명CMV간염여담총관낭종역유밀절관계.
One hundred eighyt-two infants suffering from HBsAg negative infantile hepatitis syndrome with jaundice,hepatosplenomegaly and high level of SGPT were virologically studied.Ninety-two(50.55%)cases wero found cytomegalovirus(CMV)positive by virus isolation and/or serologic test.CMV could be isolated from the saliva and breast milk aS well aS the urine.It was demonstrated that the secretion of CMV in urine might persist for a long period of time,and might be intermittent.OMV had been isolated from a liver biopsy and an autopsy liver specimen of infants suffering from biliary atresia.The inflrmmatory theory of bi]iary atresia was thus proved.These find ings illustrated that biliury atresia might be developed in infantile hepatitis.In addition.CMV had also been isolated from liver biopsy 0f another infant suffering from eholedochal cyst.It showed that there was also a close zelationship between OMV hepatitis and choledochal cyst.