CAJ | 학술논문

目的探讨肺癌治疗与真菌感染之间的关系.方法 2083例肺癌患者按治疗方法分别进行分组,包括手术与非手术组,放疗组、化疗组和放疗化疗组,治疗感染组和预防感染组.分析各治疗方法中导致真茵感染因素并做统计学处理.结果肺癌患者的真茵感染率14.16%,手术组与非手术组感染率无统计学意义(P＞0.05),手术组内Ⅲ、Ⅳ期之间有统计学意义(P＜0.01),Ⅲ、Ⅳ期手术组和非手术组有统计学意义(P＜0.01),化疗组,放疗化疗组与放疗组有统计学意义(P＜0.05),化疗组和放疗化疗组无统计学意义(P＞0.05),治疗感染组和预防感染组有统计学意义(P＜0.05),治疗感染组和预防感染组内随着联合用药的增加差异有统计学意义(P＜0.01).结论肺癌患者Ⅲ、Ⅳ期手术,化疗,联合应用抗生素,激素、导管侵入治疗可增加其真菌的感染率.
목적 탐토폐암치료여진균감염지간적관계.방법 2083례폐암환자안치료방법분별진행분조,포괄수술여비수술조,방료조、화료조화방료화료조,치료감염조화예방감염조.분석각치료방법중도치진인감염인소병주통계학처리.결과 폐암환자적진인감염솔14.16%,수술조여비수술조감염솔무통계학의의(P＞0.05),수술조내Ⅲ、Ⅳ기지간유통계학의의(P＜0.01),Ⅲ、Ⅳ기수술조화비수술조유통계학의의(P＜0.01),화료조,방료화료조여방료조유통계학의의(P＜0.05),화료조화방료화료조무통계학의의(P＞0.05),치료감염조화예방감염조유통계학의의(P＜0.05),치료감염조화예방감염조내수착연합용약적증가차이유통계학의의(P＜0.01).결론 폐암환자Ⅲ、Ⅳ기수술,화료,연합응용항생소,격소、도관침입치료가증가기진균적감염솔.
Objective To analyze the correlation between lung cancer treatment and fungal infection.Methods Altogether 2083 patients with lung cancer were enrolled in this retrospective study.The patients wereclassified by methods of therapy,including operative group and non-operative group,antibiotic group and non-antibiotic group,radiotherapy group,chemotherapy group,radiochemotherapy group,hormone group and cathetertherapy group.Results Out of the 2083 patients,14.16%were diagnosed of airway fungal infection.The differenceof infection rate was not significant between operation group and non-operation group(P＞0.05).Among the operationgroup,the Ⅳ phase cancer patients had significantly higher infection rate than Ⅲ phase patients(P＜0.01).Thepatients who had received chemotherapy,or combination of chemotherapy and radiotherapy had a higher infection ratethan those who received radiotherapy only(P＜0.05).Those who received antimierobial treatment had a higherinfection rate than those who received antimicrobial propbylaxis(P＜0.05).Specifically,the more antimicrobials Wasused,the more significant the difference was(P＜0.01).Conclusion The incidence of fungal infection in lungcancer patients is related to the use of antibiotics,chemotherapy,operation,hormone therapy and catheter therapy.