中华放射医学与防护杂志
中華放射醫學與防護雜誌
중화방사의학여방호잡지
Chinese Journal of Radiological Medicine and Protection
2012年
4期
403-406
,共4页
赵风玲%傅宝华%陈玉浩%吕玉民
趙風玲%傅寶華%陳玉浩%呂玉民
조풍령%부보화%진옥호%려옥민
过量照射%远期辐射效应%随访
過量照射%遠期輻射效應%隨訪
과량조사%원기복사효응%수방
Overexposure%Long-term health effect%Follow-up
目的 探讨过量受照人员的远期健康效应.方法 对25例受照剂量为0.10～0.33 Gy的人员,进行照后32 ～41年的医学随访.观察临床表现、眼晶状体、细胞遗传学指标、免疫功能、内分泌功能等指标的变化.结果 受照者无力型神经衰弱症状发生率高.2例分别患肝癌、食管癌；7例出现晶状体后囊下点状混浊,1例疑似放射性白内障；外周血淋巴细胞染色体畸变率和微核率显著高于对照组(x2=8.88、8.71、40.60、45.63,P＜0.05)；受照组血清IgG平均值显著高于对照组(t =2.16,P＜0.05),IgM平均值显著低于对照组(t=2.03,P＜0.05)；受照组血清三碘甲状腺原氨酸(T3)、甲状腺素(T.)、促甲状腺素( TSH)平均值均在正常范围,但显著低于对照组(t=2.40、3.54、2.13,P＜0.05).结论 过量照射对晶状体、免疫系统、细胞遗传学指标存在一定的影响,观察过量受照人员的远期医学效应有重要意义.
目的 探討過量受照人員的遠期健康效應.方法 對25例受照劑量為0.10～0.33 Gy的人員,進行照後32 ～41年的醫學隨訪.觀察臨床錶現、眼晶狀體、細胞遺傳學指標、免疫功能、內分泌功能等指標的變化.結果 受照者無力型神經衰弱癥狀髮生率高.2例分彆患肝癌、食管癌；7例齣現晶狀體後囊下點狀混濁,1例疑似放射性白內障；外週血淋巴細胞染色體畸變率和微覈率顯著高于對照組(x2=8.88、8.71、40.60、45.63,P＜0.05)；受照組血清IgG平均值顯著高于對照組(t =2.16,P＜0.05),IgM平均值顯著低于對照組(t=2.03,P＜0.05)；受照組血清三碘甲狀腺原氨痠(T3)、甲狀腺素(T.)、促甲狀腺素( TSH)平均值均在正常範圍,但顯著低于對照組(t=2.40、3.54、2.13,P＜0.05).結論 過量照射對晶狀體、免疫繫統、細胞遺傳學指標存在一定的影響,觀察過量受照人員的遠期醫學效應有重要意義.
목적 탐토과량수조인원적원기건강효응.방법 대25례수조제량위0.10～0.33 Gy적인원,진행조후32 ～41년적의학수방.관찰림상표현、안정상체、세포유전학지표、면역공능、내분비공능등지표적변화.결과 수조자무력형신경쇠약증상발생솔고.2례분별환간암、식관암；7례출현정상체후낭하점상혼탁,1례의사방사성백내장；외주혈림파세포염색체기변솔화미핵솔현저고우대조조(x2=8.88、8.71、40.60、45.63,P＜0.05)；수조조혈청IgG평균치현저고우대조조(t =2.16,P＜0.05),IgM평균치현저저우대조조(t=2.03,P＜0.05)；수조조혈청삼전갑상선원안산(T3)、갑상선소(T.)、촉갑상선소( TSH)평균치균재정상범위,단현저저우대조조(t=2.40、3.54、2.13,P＜0.05).결론 과량조사대정상체、면역계통、세포유전학지표존재일정적영향,관찰과량수조인원적원기의학효응유중요의의.
Objective To explore the long-term health effects of overexpose to radiation.Methods The 32 -41-year medical followed-up observations were performed for 25 persons exposed to ionizing radiation in the dose range of 0.10 -0.33 Gy. Observations were made of clinical symptom,eye lens,cytogenetics,immune function and endocrine function for these persons. Results The incidence of neurasthenic symptom was higher in exposed group than that in control group.2 cases suffered from liver cancer and esophageal cancer,respectively. Posterior capsule punctate phacoscotasmus of the lens wereobserved in 7 cases.There was I case of cataract in the exposed group. The frequencies of chromosomeaberration and micronucleis in peripheral blood lymphocyte in the exposed group were significantly higherthan those in control group (x2 =8.88,8.71,40.60,45.63,P ＜ 0.05 ).The average value of serum IgG was higher(t =2.16,P ＜0.05 ),while that of IgM was obviously lower in the exposed group (t =2.03,P ＜0.05).The average values of serum triiodothyronine (T3),thyroxine (T4 ) and thyroid-stimulating hormone (TSH) in the exposed group were obviously lower than those in the control group (t =2.40,3.54,2.13,P ＜0.05 ).Conclusions Overexposure has effect on lens,immune function,cytogenetics to some degree.It is important to observe the long-term health effect on overexposed persons.
