中华航空航天医学杂志
中華航空航天醫學雜誌
중화항공항천의학잡지
CHINESE JOURNAL OF AEROSPACE MEDICINE
2011年
4期
270-273
,共4页
王妍%熊浩伟%李婷%周毓瑾
王妍%熊浩偉%李婷%週毓瑾
왕연%웅호위%리정%주육근
瘦素%脂肪肝%血糖%胆固醇%甘油三酯类%脂蛋白类,HDL
瘦素%脂肪肝%血糖%膽固醇%甘油三酯類%脂蛋白類,HDL
수소%지방간%혈당%담고순%감유삼지류%지단백류,HDL
Leptin%Fatty liver%Blood glucose%Cholesterol%Triglycerides%Lipoproteins,HDL
目的 分析2009年4月至2010年7月在民航广州医院航空体检中心体检的民航60例现役非酒精性脂肪肝(nonalcoholic fatty liver disease,NAFLD)飞行员血清瘦素、血糖、血脂的变化,探讨飞行员患NAFLD的危险因素及其预防措施. 方法 60例NAFLD飞行员作为试验组,体检结论正常的60例飞行员作为对照组.询问病史,空腹测量身高、体重、腰围、臀围及血压；检测血脂、空腹血糖(fasting plasma glucose,FPG)和血清瘦素水平,并进行组间比较. 结果 NAFLD组体重指数(body mass index,BMI)、腰臀比、收缩压、舒张压、甘油三酯(triglyceride,TG)和血清瘦素水平较对照组显著上升(t=-4.62～12.20,P＜0.01);FPG较对照组上升(t=2.63,P＜0.05)；高密度脂蛋白胆固醇(high density lipid-cholesterol,HDL-C)明显下降(t=3.65,P＜o.01).瘦素水平与TG、FPG呈正相关(r=0.72、0.82,P＜0.05),与HDL-C呈负相关(r=-0.62,P＜0.05). 结论 飞行员患NAFLD与其饮食结构及活动减少造成肥胖有关,并与瘦素水平升高密切关联.应加强对患NAFLD飞行员的预防和治疗工作,为飞行员的健康和飞行安全提供保障.
目的 分析2009年4月至2010年7月在民航廣州醫院航空體檢中心體檢的民航60例現役非酒精性脂肪肝(nonalcoholic fatty liver disease,NAFLD)飛行員血清瘦素、血糖、血脂的變化,探討飛行員患NAFLD的危險因素及其預防措施. 方法 60例NAFLD飛行員作為試驗組,體檢結論正常的60例飛行員作為對照組.詢問病史,空腹測量身高、體重、腰圍、臀圍及血壓；檢測血脂、空腹血糖(fasting plasma glucose,FPG)和血清瘦素水平,併進行組間比較. 結果 NAFLD組體重指數(body mass index,BMI)、腰臀比、收縮壓、舒張壓、甘油三酯(triglyceride,TG)和血清瘦素水平較對照組顯著上升(t=-4.62～12.20,P＜0.01);FPG較對照組上升(t=2.63,P＜0.05)；高密度脂蛋白膽固醇(high density lipid-cholesterol,HDL-C)明顯下降(t=3.65,P＜o.01).瘦素水平與TG、FPG呈正相關(r=0.72、0.82,P＜0.05),與HDL-C呈負相關(r=-0.62,P＜0.05). 結論 飛行員患NAFLD與其飲食結構及活動減少造成肥胖有關,併與瘦素水平升高密切關聯.應加彊對患NAFLD飛行員的預防和治療工作,為飛行員的健康和飛行安全提供保障.
목적 분석2009년4월지2010년7월재민항엄주의원항공체검중심체검적민항60례현역비주정성지방간(nonalcoholic fatty liver disease,NAFLD)비행원혈청수소、혈당、혈지적변화,탐토비행원환NAFLD적위험인소급기예방조시. 방법 60례NAFLD비행원작위시험조,체검결론정상적60례비행원작위대조조.순문병사,공복측량신고、체중、요위、둔위급혈압；검측혈지、공복혈당(fasting plasma glucose,FPG)화혈청수소수평,병진행조간비교. 결과 NAFLD조체중지수(body mass index,BMI)、요둔비、수축압、서장압、감유삼지(triglyceride,TG)화혈청수소수평교대조조현저상승(t=-4.62～12.20,P＜0.01);FPG교대조조상승(t=2.63,P＜0.05)；고밀도지단백담고순(high density lipid-cholesterol,HDL-C)명현하강(t=3.65,P＜o.01).수소수평여TG、FPG정정상관(r=0.72、0.82,P＜0.05),여HDL-C정부상관(r=-0.62,P＜0.05). 결론 비행원환NAFLD여기음식결구급활동감소조성비반유관,병여수소수평승고밀절관련.응가강대환NAFLD비행원적예방화치료공작,위비행원적건강화비행안전제공보장.
Objective To investigate the changes of serum leptin,blood glucose and blood lipid of the civil pilot with nonalcoholic fatty liver disease (NAFLD) and to discuss the risk factors of NAFLD and related prevention measures. Method Sixty pilots with NAFLD and 60 normal pilots were respectively selected as NAFLD and control group.Their body mass index (BMI),waist-to-hip ratio (WHR),blood pressure,blood lipid,fasting plasma glucose (FPG),triglyceride (TG),high density lipid-cholesterol (HDL-C) and serum leptin were tested and compared. Result The BMI,WHR,systolic/diastolic blood pressure,TG and serum leptin in NAFLD group were significantly higher than those in normal control group (t=4.62-12.20,P＜0.01),FPG was higher than that in normal control group (t=2.63,P＜0.05),the HDL-C in NAFLD group was significantly lower than that in normal control group (t=3.65,P＜0.01).Serum leptin was positively correlated with TG and FPG (r=-0.72,0.82,P＜0.05) and serum leptin was negatively correlated with HDL-C (r=-0.62,P＜0.05). Conclusions Pilot's NAFLD is related with the obesity caused by unhealthy diet and less exercise and closely related with high level of leptin.More attention should be paid on prevention and treatment of the pilots with NAFLD so to ensure the health of pilots and flight safety.
