生物化学与生物物理进展
生物化學與生物物理進展
생물화학여생물물리진전
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
2001年
2期
263-266
,共4页
张成岗%欧阳曙光%张绍文%瞿祥虎%鱼咏涛%周钢桥%吴松锋%贺福初
張成崗%歐暘曙光%張紹文%瞿祥虎%魚詠濤%週鋼橋%吳鬆鋒%賀福初
장성강%구양서광%장소문%구상호%어영도%주강교%오송봉%하복초
PC机%Linux操作系统%Phred/Phrap/Consed软件%Blast软件,生物信息学%大规模测序
PC機%Linux操作繫統%Phred/Phrap/Consed軟件%Blast軟件,生物信息學%大規模測序
PC궤%Linux조작계통%Phred/Phrap/Consed연건%Blast연건,생물신식학%대규모측서
personal computer%Linux operating system%Phred/Phrap/Consed software%Blast software%bioinformatics%large-scale DNA sequencing
基于PC机和Linux操作系统, 利用Phred/Phrap/Consed软件和Blast软件, 构建了核酸序列大规模自动分析系统. 该套系统可自动完成从测序峰图向核酸序列的转化、载体序列去除、序列自动拼接、重复序列鉴定以及序列的相似性分析, 可加速对大规模测序数据的分析和利用.
基于PC機和Linux操作繫統, 利用Phred/Phrap/Consed軟件和Blast軟件, 構建瞭覈痠序列大規模自動分析繫統. 該套繫統可自動完成從測序峰圖嚮覈痠序列的轉化、載體序列去除、序列自動拼接、重複序列鑒定以及序列的相似性分析, 可加速對大規模測序數據的分析和利用.
기우PC궤화Linux조작계통, 이용Phred/Phrap/Consed연건화Blast연건, 구건료핵산서렬대규모자동분석계통. 해투계통가자동완성종측서봉도향핵산서렬적전화、재체서렬거제、서렬자동병접、중복서렬감정이급서렬적상사성분석, 가가속대대규모측서수거적분석화이용.
More and more DNA sequences have been obtained since the start-up of human genome project. Powerful system is badly needed for data mining on these DNA sequences. Based on a personal computer and Linux operating system, the Phred/Phrap/Consed software and Blast software were used to construct a platform for batch analysis of the sequences, including identifying raw DNA sequence from chromatogram file, vector sequence removing, contig analysis (sequence assembly), repeat sequence identifying and sequence similarity analysis. Result demonstrated that this robust platform could accelerate data analysis for large-scale DNA sequencing.
