CAJ | 학술논문

目的:探讨急性中度低压缺氧对飞行员血浆血管紧张素Ⅱ (AⅡ )及肾上腺髓质素 (ADM)含量的影响. 方法:用放射免疫法测定了 16名健康男性歼击机飞行员缺氧前、急性中度低压缺氧后即刻及到达地面 6 h后的血浆 AⅡ及 ADM的含量,并以 16名健康男性地面人员相应时间的测定作对照. 结果:①缺氧前飞行员的血浆 AⅡ及 ADM含量 [(72.56± 4.69),( 48.81± 3.68) ng/L]与对照组 [(69.60± 4.58),(46.43± 3.45) ng/L]比较,差异无显著性意义 (P >0.05).②急性中度低压缺氧后即刻,飞行员的血浆 AⅡ及 ADM含量 [(77.68± 5.18),(52.72± 4.13 )ng/L]较缺氧前明显增加 (P< 0.05),缺氧结束后 6 h[(74.03± 4.88),(48.72± 3.64) ng/L]恢复到缺氧前水平. 结论:急性中度低压缺氧可导致飞行员血浆 AⅡ及 ADM的含量增加 ,这种影响是一过性的.
목적:탐토급성중도저압결양대비행원혈장혈관긴장소Ⅱ (AⅡ )급신상선수질소 (ADM)함량적영향. 방법:용방사면역법측정료 16명건강남성섬격궤비행원결양전、급성중도저압결양후즉각급도체지면 6 h후적혈장 AⅡ급 ADM적함량,병이 16명건강남성지면인원상응시간적측정작대조. 결과:①결양전비행원적혈장 AⅡ급 ADM함량 [(72.56± 4.69),( 48.81± 3.68) ng/L]여대조조 [(69.60± 4.58),(46.43± 3.45) ng/L]비교,차이무현저성의의 (P >0.05).②급성중도저압결양후즉각,비행원적혈장 AⅡ급 ADM함량 [(77.68± 5.18),(52.72± 4.13 )ng/L]교결양전명현증가 (P< 0.05),결양결속후 6 h[(74.03± 4.88),(48.72± 3.64) ng/L]회복도결양전수평. 결론:급성중도저압결양가도치비행원혈장 AⅡ급 ADM적함량증가 ,저충영향시일과성적.
AIM:To explore the effects of acute moderate hypobaric hypoxia(AMHH) on plasma angiotension Ⅱ (AⅡ ) and adreomedullin(ADM) content in pilots. METHODS:The concentrations of plasma AⅡ and ADM were measured by radioimmunoassay in 16 healthy male pilots before hypoxia,at the moment of AMHH and 6 hours after returning to the ground.A total of 16 healthy male ground crews were set as control group,and their plasma AⅡ and ADM contents were assayed at corresponding time. CONCLUSION:AMHH can induce temporary increase of plasma AⅡ and ADM in pilots.