中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2011年
z1期
17-19
,共3页
疱疹,带状%T淋巴细胞亚群%复方甘草酸苷
皰疹,帶狀%T淋巴細胞亞群%複方甘草痠苷
포진,대상%T림파세포아군%복방감초산감
Herpes zoster%T-Lymphocyte subsets%Compound glycyrrhizin
目的 观察复方甘草酸苷辅助治疗对带状疱疹患者外周血T细胞亚群的影响.方法 93例诊断为带状疱疹的患者随机分为对照组46例和复方甘草酸苷辅助治疗组47例,对照组单纯抗病毒治疗,治疗组在抗病毒治疗治疗基础上加用复方甘草酸苷治疗.所有患者于治疗前后,采用流式细胞仪对患者外周血T细胞亚群的表达水平进行检测和比较.结果 两组患者治疗后T细胞亚群CD3、CD4 CD8、CD4/CD8比值的表达水平差异均有统计学意义(均P＜0.05).结论 复方甘草酸苷辅助治疗不仅能缩短患者止疱、止痛、结痂和痊愈时间,减少后遗神经痛的发生,而且能影响患者T细胞亚群的表达,改善患者的细胞免疫功能.
目的 觀察複方甘草痠苷輔助治療對帶狀皰疹患者外週血T細胞亞群的影響.方法 93例診斷為帶狀皰疹的患者隨機分為對照組46例和複方甘草痠苷輔助治療組47例,對照組單純抗病毒治療,治療組在抗病毒治療治療基礎上加用複方甘草痠苷治療.所有患者于治療前後,採用流式細胞儀對患者外週血T細胞亞群的錶達水平進行檢測和比較.結果 兩組患者治療後T細胞亞群CD3、CD4 CD8、CD4/CD8比值的錶達水平差異均有統計學意義(均P＜0.05).結論 複方甘草痠苷輔助治療不僅能縮短患者止皰、止痛、結痂和痊愈時間,減少後遺神經痛的髮生,而且能影響患者T細胞亞群的錶達,改善患者的細胞免疫功能.
목적 관찰복방감초산감보조치료대대상포진환자외주혈T세포아군적영향.방법 93례진단위대상포진적환자수궤분위대조조46례화복방감초산감보조치료조47례,대조조단순항병독치료,치료조재항병독치료치료기출상가용복방감초산감치료.소유환자우치료전후,채용류식세포의대환자외주혈T세포아군적표체수평진행검측화비교.결과 량조환자치료후T세포아군CD3、CD4 CD8、CD4/CD8비치적표체수평차이균유통계학의의(균P＜0.05).결론 복방감초산감보조치료불부능축단환자지포、지통、결가화전유시간,감소후유신경통적발생,이차능영향환자T세포아군적표체,개선환자적세포면역공능.
Objective To study the influence on T-lymphocyte subsets in herpes zoster with adjuvant treatment of compound glycyrrhizin.Methods 93 patients with herpes zoster were randomly divided into two groups:control group(46 cases,treated with antiviral drugs) and 1 treatment group(47 cases,treated with compound glycyrrhizin and antiviral drugs).The expression of T-lymphocyte subsets on the T cell surface in patients and control group were determined by flow cytometry.Results The expression of CD3,CD4,CD8,CD4/CD8 ratio was significantly different in the treatment group and control group.Conclusion Compound glycyrrhizic adjuvant therapy could not only shorten check blister,acetanilide,scar tissue and recovery time,reduce the sequela of neuralgia,but also affect the expression state of T lymphocyte subsets with herpes zoster,improve the cellular immune function with herpes zoster.
