CAJ | 학술논문

目的应用回声追踪技术探讨围绝经期妇女行雌激素替代治疗后颈动脉壁弹性特征.方法围绝经期雌二醇下降者82例,随机分为治疗组(克龄蒙)和对照组各41例,治疗前及治疗后6个月应用回声追踪技术评估颈动脉硬化参数,包括压力应变弹性系数(Ep)、硬化参数(β)、顺应性(AC)、脉搏波传导速度(PWVβ)和增大指数(AI).结果治疗组Ep、β、PWVβ、AI较对照组明显降低,AC明显增高(P＜0.05).结论回声追踪技术能够简便、快速地判断围绝经期妇女行雌激素替代治疗后动脉弹性变化,客观定量评价雌激素替代治疗疗效.
목적 응용회성추종기술탐토위절경기부녀행자격소체대치료후경동맥벽탄성특정.방법 위절경기자이순하강자82례,수궤분위치료조(극령몽)화대조조각41례,치료전급치료후6개월응용회성추종기술평고경동맥경화삼수,포괄압력응변탄성계수(Ep)、경화삼수(β)、순응성(AC)、맥박파전도속도(PWVβ)화증대지수(AI).결과 치료조Ep、β、PWVβ、AI교대조조명현강저,AC명현증고(P＜0.05).결론 회성추종기술능구간편、쾌속지판단위절경기부녀행자격소체대치료후동맥탄성변화,객관정량평개자격소체대치료료효.
Objective To study the change of early carotid elasticity in perimenopausal women treated by hormone replacement therapy using e-tracking technique. Methods A total of 82 perimenopausal women with lower level of estradiol were randomly divided into two groups:41 cases in the treatment group and 41cases in the control group. Postmenopausal women in the treatment group were treated with Climnen. Before and 6 months after estrogen therapy,e-tracking technique was used to evaluate the carotid elastic modulus,such as the stiffness parameters (β), pressure-strain elastic modulus ( Ep), arterial compliances (AC), pulse wave conducting velocity (PWVβ) and augment index(AI). Results Compared with the normal group,datas of Ep,β,PWVβ and AI were significantly lower in treated group, while AC was obviously higher ( P ＜0.01). Conclusions E-tracking technique is a quick, simple and high accurate evaluating method for the change of carotid elasticity in perimenopausal women.