国际中医中药杂志
國際中醫中藥雜誌
국제중의중약잡지
INTERNATIONAL JOURNAL OF TRIDITIONAL CHINESE MEDICINE
2011年
6期
491-493
,共3页
血必净注射液%慢性阻塞性肺病急性加重期%超敏C%反应蛋白
血必淨註射液%慢性阻塞性肺病急性加重期%超敏C%反應蛋白
혈필정주사액%만성조새성폐병급성가중기%초민C%반응단백
Xuebi-jing injectiong%Acute exacerbation of chronic obstructive pulmonary disease%High-sensitivity C-reactive protein
目的 观察慢性阻塞性肺疾病急性发作期(chronic obstructive pulmonary disease,AECOPD)超敏C 反应蛋白(hs-CRP)水平的变化及血必净对其的影响.方法 将86 例AECOPD 患者按随机数字表法分为两组各43 例,对照组采用常规疗法治疗,治疗组在对照组治疗基础上加用血必净,两组患者分别于入院当天及治疗后5 d 检测血清hs-CRP,并结合患者血细胞、血气分析和APACHE Ⅱ评分,进行分析和比较.结果 治疗前两组血清hs-CRP 水平无明显差异,治疗后两组血清hs-CRP 水平均降低,治疗组降低尤为明显(t＝5.3302,P＜0.01),治疗后两组血细胞、血气分析及APACHEⅡ评分均有改善,治疗组治疗后白细胞、中性粒细胞、APACHE Ⅱ与对照组比较,差异有统计学意义(t 值分别为:13.5089、26.3077 、13.4053,P 均＜0.01).结论 在常规治疗基础上联用血必净可改善血清hs-CRP 水平,提高慢性阻塞性肺疾病急性加重期的疗效.
目的 觀察慢性阻塞性肺疾病急性髮作期(chronic obstructive pulmonary disease,AECOPD)超敏C 反應蛋白(hs-CRP)水平的變化及血必淨對其的影響.方法 將86 例AECOPD 患者按隨機數字錶法分為兩組各43 例,對照組採用常規療法治療,治療組在對照組治療基礎上加用血必淨,兩組患者分彆于入院噹天及治療後5 d 檢測血清hs-CRP,併結閤患者血細胞、血氣分析和APACHE Ⅱ評分,進行分析和比較.結果 治療前兩組血清hs-CRP 水平無明顯差異,治療後兩組血清hs-CRP 水平均降低,治療組降低尤為明顯(t＝5.3302,P＜0.01),治療後兩組血細胞、血氣分析及APACHEⅡ評分均有改善,治療組治療後白細胞、中性粒細胞、APACHE Ⅱ與對照組比較,差異有統計學意義(t 值分彆為:13.5089、26.3077 、13.4053,P 均＜0.01).結論 在常規治療基礎上聯用血必淨可改善血清hs-CRP 水平,提高慢性阻塞性肺疾病急性加重期的療效.
목적 관찰만성조새성폐질병급성발작기(chronic obstructive pulmonary disease,AECOPD)초민C 반응단백(hs-CRP)수평적변화급혈필정대기적영향.방법 장86 례AECOPD 환자안수궤수자표법분위량조각43 례,대조조채용상규요법치료,치료조재대조조치료기출상가용혈필정,량조환자분별우입원당천급치료후5 d 검측혈청hs-CRP,병결합환자혈세포、혈기분석화APACHE Ⅱ평분,진행분석화비교.결과 치료전량조혈청hs-CRP 수평무명현차이,치료후량조혈청hs-CRP 수평균강저,치료조강저우위명현(t＝5.3302,P＜0.01),치료후량조혈세포、혈기분석급APACHEⅡ평분균유개선,치료조치료후백세포、중성립세포、APACHE Ⅱ여대조조비교,차이유통계학의의(t 치분별위:13.5089、26.3077 、13.4053,P 균＜0.01).결론 재상규치료기출상련용혈필정가개선혈청hs-CRP 수평,제고만성조새성폐질병급성가중기적료효.
Objective To investigate the effect of Xuebi-jing injection on the change of the serum high-sensitivity C-reactive protein (hs-CRP) in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD). Methods 86 patients with AECOPD were enrolled in this study, who was randomly divided into a control group (43 cases)and a treatment group (43 cases). Both treatment group and control group were given conventional therapy. On this basis, Xuebi-jing injection was added to the treatment group. Hs-CRP, blood gas analysis, blood cell count and severity of illness score (acute physiological and chronic health evaluation Ⅱ, APACHE Ⅱ) were monitored before and 5 days after treatment. Results There was no obvious difference of hs-CRP levels between two groups before treatment. Hs-CRP was decreased in both groups after the treatment, while the treatment group showed an obvious decrease compared with the control group (t＝5.3302,P＜0.01). Blood gas analysis, blood cecount, APACHE Ⅱ scores were improved after the treatment in both groups, while the improvement in treatment group showed obvious difference than the control group (t＝13.5089、26.3077 、13.4053,P＜0.01). Conclusion The conventional therapy plus Xuebi-jing injectiong for AECOPD can improve serum hs-CRP levels and improve the efficacy of AECOPD .
