中华预防医学杂志
中華預防醫學雜誌
중화예방의학잡지
CHINESE JOURNAL OF
2011年
7期
601-604
,共4页
黄彦钦%蔡善荣%张苏展%李其龙%马新源%何玉芳%周晓红%郑树
黃彥欽%蔡善榮%張囌展%李其龍%馬新源%何玉芳%週曉紅%鄭樹
황언흠%채선영%장소전%리기룡%마신원%하옥방%주효홍%정수
结直肠肿瘤%早期诊断%普查%方案评价
結直腸腫瘤%早期診斷%普查%方案評價
결직장종류%조기진단%보사%방안평개
Colorectal neoplasms%Early diagnosis%Mass screening%Program evaluation
目的 评价现行结直肠癌筛查方案的肿瘤检出率,探讨方案的应用价值.方法 筛查目标为2007-2009年杭州下城区和嘉善县40~74岁户籍人口,共43 713名.先进行由问卷调查与大便潜血检测组成的初筛,阳性者进行结肠镜诊断性复筛,发现息肉样病变即取活检或摘除,病理确诊.分析筛查数据,计算初筛阳性人群(高危人群)中不同年龄段和不同性别人群的肿瘤检出率.结果 初筛认定结直肠癌高危人群6489名,占14.85%.共有完成结肠镜检查4701名,检出结直肠肿瘤569例,检出率为12.10%(95%CI:11.17%～13.04%).其中结直肠癌52例,检出率1.11% (95%CI:0.81%～1.41%);进展期腺瘤(183 例)和非进展期腺瘤(334例)检出率分别为3.89%(95%CI:3.34%～4.45%)和7.10%(95%CI:6.37%～7.84%).70～74岁男性肿瘤检出率最高,为22.81%(95%CI:16.98%～28.70%);40～44岁女性中检出率最低,为2.49%(95%CI:0.79%～4.20%).结论 我国现行结直肠癌人群筛查方案的应用效果较好,但方案仍需进一步完善.
目的 評價現行結直腸癌篩查方案的腫瘤檢齣率,探討方案的應用價值.方法 篩查目標為2007-2009年杭州下城區和嘉善縣40~74歲戶籍人口,共43 713名.先進行由問捲調查與大便潛血檢測組成的初篩,暘性者進行結腸鏡診斷性複篩,髮現息肉樣病變即取活檢或摘除,病理確診.分析篩查數據,計算初篩暘性人群(高危人群)中不同年齡段和不同性彆人群的腫瘤檢齣率.結果 初篩認定結直腸癌高危人群6489名,佔14.85%.共有完成結腸鏡檢查4701名,檢齣結直腸腫瘤569例,檢齣率為12.10%(95%CI:11.17%～13.04%).其中結直腸癌52例,檢齣率1.11% (95%CI:0.81%～1.41%);進展期腺瘤(183 例)和非進展期腺瘤(334例)檢齣率分彆為3.89%(95%CI:3.34%～4.45%)和7.10%(95%CI:6.37%～7.84%).70～74歲男性腫瘤檢齣率最高,為22.81%(95%CI:16.98%～28.70%);40～44歲女性中檢齣率最低,為2.49%(95%CI:0.79%～4.20%).結論 我國現行結直腸癌人群篩查方案的應用效果較好,但方案仍需進一步完善.
목적 평개현행결직장암사사방안적종류검출솔,탐토방안적응용개치.방법 사사목표위2007-2009년항주하성구화가선현40~74세호적인구,공43 713명.선진행유문권조사여대편잠혈검측조성적초사,양성자진행결장경진단성복사,발현식육양병변즉취활검혹적제,병리학진.분석사사수거,계산초사양성인군(고위인군)중불동년령단화불동성별인군적종류검출솔.결과 초사인정결직장암고위인군6489명,점14.85%.공유완성결장경검사4701명,검출결직장종류569례,검출솔위12.10%(95%CI:11.17%～13.04%).기중결직장암52례,검출솔1.11% (95%CI:0.81%～1.41%);진전기선류(183 례)화비진전기선류(334례)검출솔분별위3.89%(95%CI:3.34%～4.45%)화7.10%(95%CI:6.37%～7.84%).70～74세남성종류검출솔최고,위22.81%(95%CI:16.98%～28.70%);40～44세녀성중검출솔최저,위2.49%(95%CI:0.79%～4.20%).결론 아국현행결직장암인군사사방안적응용효과교호,단방안잉수진일보완선.
Objective To evaluate a colorectal cancer screening program by tumor detection rate and discussing its application values.Method In total,43 713 subjects were recruited in the screening program who were the registered people aged 40-74 in Xiacheng and Jiashan during year 2007-2009.The first screening involved questionnaire survey of colorectal cancer related risk factors and fecal occult blood test (FOBT),colonoscopy was performed when a positive result was observed in the first screening.If polyps were found during colonoscopy,biopsy and pathological diagnosis were carried out.The screening data were analyzed and the tumor detection rate was calculated according to age or sex.Results 6489 subjects (14.85%) belonged to the high risk group of colorectal cancer in the first screening,in which 4701 subjects finished complete colonoscopy.Finally,569 colorectal neoplasm were diagnosed,the detection rate was 12.10% (95%CI:11.17%-13.04%).It included 52 colorectal cancer (1.11%,95%CI:0.81%-1.41%),183 advanced adenoma(3.89%,95%CI: 3.34%-4.45%),334 non-advanced adenoma (7.10%,95%CI: 6.37%-7.84%).The highest detective rate was observed in male group that aged 70-74 (22.81%,95%CI: 16.98%-28.70%),the lowest detective rate was observed in female group aged 40-44 (2.49%,95%CI: 0.79%-4.20%).Conclusion The current colorectal cancer screening program in China works well,but the revision of the program is necessary.
