中华消化内镜杂志
中華消化內鏡雜誌
중화소화내경잡지
CHINESE JOURNAL OF DIGESTIVE ENDOSCOPY
2008年
12期
639-642
,共4页
赖少清%张宏图%张月明%贺舜%鞠凤环%于桂香%倪晓光%李晓燕%王贵齐
賴少清%張宏圖%張月明%賀舜%鞠鳳環%于桂香%倪曉光%李曉燕%王貴齊
뢰소청%장굉도%장월명%하순%국봉배%우계향%예효광%리효연%왕귀제
食管炎%单纯疱疹病毒%食管溃疡
食管炎%單純皰疹病毒%食管潰瘍
식관염%단순포진병독%식관궤양
Esophagitis%Herpes simplex virus%Esophagus ulcer
目的 探讨病毒性食管炎内镜和病理表现特点以及病因检测方法 .方法 回顾分析16例病毒性食管炎的临床资料,内镜、病理及免疫组化检查结果 .结果 16例病毒性食管炎内镜下表现为单发或多发性食管溃疡,溃疡灶集中在食管胸上、中段.溃疡表浅为较规则的圆形或椭圆形,溃疡面清洁,与周围组织界限清楚.病理学表现为特征为鳞状上皮黏膜内有退变坏死组织,伴溃疡形成,大量中性粒细胞和淋巴细胞浸润,毛细血管增生,肉芽组织形成,基底细胞反应性增生.16例患者活检组织的蜡块标本单纯疱疹病毒检测结果 阳性,巨细胞病毒、EB病毒、疱疹病毒8型均为阴性.结论 毒性食管炎具有特殊的内镜和病理表现,对活检标本进行免疫组化检测能够确定病因.
目的 探討病毒性食管炎內鏡和病理錶現特點以及病因檢測方法 .方法 迴顧分析16例病毒性食管炎的臨床資料,內鏡、病理及免疫組化檢查結果 .結果 16例病毒性食管炎內鏡下錶現為單髮或多髮性食管潰瘍,潰瘍竈集中在食管胸上、中段.潰瘍錶淺為較規則的圓形或橢圓形,潰瘍麵清潔,與週圍組織界限清楚.病理學錶現為特徵為鱗狀上皮黏膜內有退變壞死組織,伴潰瘍形成,大量中性粒細胞和淋巴細胞浸潤,毛細血管增生,肉芽組織形成,基底細胞反應性增生.16例患者活檢組織的蠟塊標本單純皰疹病毒檢測結果 暘性,巨細胞病毒、EB病毒、皰疹病毒8型均為陰性.結論 毒性食管炎具有特殊的內鏡和病理錶現,對活檢標本進行免疫組化檢測能夠確定病因.
목적 탐토병독성식관염내경화병리표현특점이급병인검측방법 .방법 회고분석16례병독성식관염적림상자료,내경、병리급면역조화검사결과 .결과 16례병독성식관염내경하표현위단발혹다발성식관궤양,궤양조집중재식관흉상、중단.궤양표천위교규칙적원형혹타원형,궤양면청길,여주위조직계한청초.병이학표현위특정위린상상피점막내유퇴변배사조직,반궤양형성,대량중성립세포화림파세포침윤,모세혈관증생,육아조직형성,기저세포반응성증생.16례환자활검조직적사괴표본단순포진병독검측결과 양성,거세포병독、EB병독、포진병독8형균위음성.결론 독성식관염구유특수적내경화병리표현,대활검표본진행면역조화검측능구학정병인.
Objective To evaluate the endoscopic and pathologic characteristics and etiological ex-amination of viral esophagitis. Methods The data of 16 patients with viral esophagitis, including endoscop-ic, pathological and immunohistochemical findings were retrospectively studied. Results Endoscopic find-ings of viral esophagitis were characterized by single or multiple round and oval ulcers, located at the upper and middle esophagus. The surface of the ulcer was clean, and the boundary was distinct. Pathologic findings included degeneration and necrosis in squamons epithelium, accompanied by ulcer, infiltration of neutrophils and lymphocytes, hyperplasia of capillaries and basal cells and formation of granulation tissues, Immunocyto-chemical examination showed HSV-1 was positive in biopses, while CMV, EBV, HHV8 were negetive. Con-dusion Viral esophagtitis exhibited distinctive endosoopic and pathological features, and etiology can be confirmed by immunohistochemical examinations.
