中国循证医学杂志
中國循證醫學雜誌
중국순증의학잡지
CHINESE JOURNAL OF EVIDENCE-BASED MEDICINE
2010年
1期
23-25
,共3页
李广杰%岳中瑾%杨克虎%田俊强%尚攀峰%包军胜%卢建中%王伟
李廣傑%嶽中瑾%楊剋虎%田俊彊%尚攀峰%包軍勝%盧建中%王偉
리엄걸%악중근%양극호%전준강%상반봉%포군성%로건중%왕위
三聚氰胺奶粉%婴幼儿%泌尿系统结石%甘肃省
三聚氰胺奶粉%嬰幼兒%泌尿繫統結石%甘肅省
삼취청알내분%영유인%비뇨계통결석%감숙성
Melamine%Infant%Urolithiasis%Obstructive renal failure%Gansu province
目的 对甘肃省三聚氰胺奶粉所致婴幼儿泌尿系结石患病情况进行调查,为制定更为有效的诊断和治疗方案提供临床依据.方法 对兰州大学第二医院等16个医疗机构收治的402例三聚氰胺奶粉所致婴幼儿泌尿系结石住院患儿的临床基本资料,血、尿生化检测,泌尿系B超、治疗方案及转归进行回顾性分析与调查.结果 402例患儿均有三聚氰胺奶粉喂养史.其中6～12月龄婴幼儿泌尿系结石发生率最高,占50%,9例患儿自行排出结石,最大结石径4 mm × 5 mm×6 mm,最小结石径0.5 mm × 0.5 mm × 1 mm,平均结石径1 mm×2 mm ×2mm.血肌酐异常30例、血尿素氮异常27例、尿隐血阳性167例、尿酸异常2例.内科治疗385例,外科治疗14例,发生梗阻性肾功能衰竭6例.结论 月龄在6个月到12个月婴幼儿食用三聚氰胺奶粉后发生泌尿系结石的风险性最大.手术治疗对结石引起的梗阻性肾功能衰竭行有效.
目的 對甘肅省三聚氰胺奶粉所緻嬰幼兒泌尿繫結石患病情況進行調查,為製定更為有效的診斷和治療方案提供臨床依據.方法 對蘭州大學第二醫院等16箇醫療機構收治的402例三聚氰胺奶粉所緻嬰幼兒泌尿繫結石住院患兒的臨床基本資料,血、尿生化檢測,泌尿繫B超、治療方案及轉歸進行迴顧性分析與調查.結果 402例患兒均有三聚氰胺奶粉餵養史.其中6～12月齡嬰幼兒泌尿繫結石髮生率最高,佔50%,9例患兒自行排齣結石,最大結石徑4 mm × 5 mm×6 mm,最小結石徑0.5 mm × 0.5 mm × 1 mm,平均結石徑1 mm×2 mm ×2mm.血肌酐異常30例、血尿素氮異常27例、尿隱血暘性167例、尿痠異常2例.內科治療385例,外科治療14例,髮生梗阻性腎功能衰竭6例.結論 月齡在6箇月到12箇月嬰幼兒食用三聚氰胺奶粉後髮生泌尿繫結石的風險性最大.手術治療對結石引起的梗阻性腎功能衰竭行有效.
목적 대감숙성삼취청알내분소치영유인비뇨계결석환병정황진행조사,위제정경위유효적진단화치료방안제공림상의거.방법 대란주대학제이의원등16개의료궤구수치적402례삼취청알내분소치영유인비뇨계결석주원환인적림상기본자료,혈、뇨생화검측,비뇨계B초、치료방안급전귀진행회고성분석여조사.결과 402례환인균유삼취청알내분위양사.기중6～12월령영유인비뇨계결석발생솔최고,점50%,9례환인자행배출결석,최대결석경4 mm × 5 mm×6 mm,최소결석경0.5 mm × 0.5 mm × 1 mm,평균결석경1 mm×2 mm ×2mm.혈기항이상30례、혈뇨소담이상27례、뇨은혈양성167례、뇨산이상2례.내과치료385례,외과치료14례,발생경조성신공능쇠갈6례.결론 월령재6개월도12개월영유인식용삼취청알내분후발생비뇨계결석적풍험성최대.수술치료대결석인기적경조성신공능쇠갈행유효.
Objective To discuss the prevalence of melamine-induced urolithiasis in infants and its development and to formulate more effective diagnosis and treatment. Methods A total of 402 cases of melamine-induced infantile urolithiasis were retrospectively analyzed with basic information, blood, urine, urinary B-mode ultrasonic diagnosis, treat-ment options and prognosis for infant urolithiasis. Results A total of 402 cases of infants had an excessive melamine milk feeding history, in which there were 9 self-discharged cases. The largest calculus diameter was 4 mm × 5 mm × 6 mm. The smallest calculus diameter was 0.5 mm × 0.5 mm × 1 mm. The average calculus diameter was 1 mm × 2 mm × 2 mm. There were 30 cases of abnormal serum creatinine, 27 of abnormal urea, 2 of abnormal uric acid, and urine occult blood positive for 167 cases. There were 395 cases which were administrated medical treatment; 7 cases were administrated sur-gical treatment; 6 cases had obstructive renal failure. Conclusion Infants whose age is more than six months but less than 12 months with a history of exposure to melamine have the larger risk of urolithiasis. B-mode ultrasonic diagnosis is practically significant on early screening urolithiasis. It is effective to perform surgical treatment for obstructive renal fail-ure caused by calculus.
