国际肿瘤学杂志
國際腫瘤學雜誌
국제종류학잡지
JOURNAL OF INTERNATIONAL ONCOLOGY
2009年
6期
472-473
,共2页
曲爱忠%梁婧%刘晓琳%李岩
麯愛忠%樑婧%劉曉琳%李巖
곡애충%량청%류효림%리암
白细胞介素6%多态性,单核苷酸%卵巢肿瘤
白細胞介素6%多態性,單覈苷痠%卵巢腫瘤
백세포개소6%다태성,단핵감산%란소종류
Interleukin-6%Polymorphism,single nueleotide%Ovarian neoplasms
临床研究发现,卵巢肿瘤患者白细胞介素(IL)-6水平明显升高,其升高能促进卵巢肿瘤的发生.IL-6升高可能是由于IL-6基因多态性影响其转录和表达.然而IL-6基因多态性与卵巢肿瘤是否具有相关性,目前尚存争议.
臨床研究髮現,卵巢腫瘤患者白細胞介素(IL)-6水平明顯升高,其升高能促進卵巢腫瘤的髮生.IL-6升高可能是由于IL-6基因多態性影響其轉錄和錶達.然而IL-6基因多態性與卵巢腫瘤是否具有相關性,目前尚存爭議.
림상연구발현,란소종류환자백세포개소(IL)-6수평명현승고,기승고능촉진란소종류적발생.IL-6승고가능시유우IL-6기인다태성영향기전록화표체.연이IL-6기인다태성여란소종류시부구유상관성,목전상존쟁의.
Clinical studies find that the level of IL-6 is significantly up-regulated in ovarian neoplasms patients. It can promote the carcinogenesis of ovarian. The up-regulation of IL-6 may be correlated with the IL-6 gene polymorphism which affects its transcription and expression. However, there is disputation in association between IL-6 gene polymorphism and ovarian neoplasms.