肿瘤研究与临床
腫瘤研究與臨床
종류연구여림상
CANCER RESEARCH AND CLINIC
2008年
4期
266-267,271
,共3页
肿瘤%药物疗法%血糖%细胞因子类
腫瘤%藥物療法%血糖%細胞因子類
종류%약물요법%혈당%세포인자류
Neoplasms%Drug therapy%Blood glucose%Cytokines
目的 探索恶性肿瘤化疗后血糖增高与细胞因子的相关性.方法 对155例恶性肿瘤患者化疗后血糖正常组、糖耐量异常组、糖尿病组细胞因子的变化情况,进行回顾性分析.结果 糖耐量异常组、糖尿病组化疗后白细胞介素-6(IL-6),肿瘤坏死因子α(TNF-α)水平较化疗前明显增高,与血糖正常组差异有统计学意义(P＜0.01),化疗后白细胞介素-10(IL-10)较化疗前增高,差异有统计学意义(P＜0.05).结论 恶性肿瘤患者化疗后血糖增高与细胞因子有密切的相关性.
目的 探索噁性腫瘤化療後血糖增高與細胞因子的相關性.方法 對155例噁性腫瘤患者化療後血糖正常組、糖耐量異常組、糖尿病組細胞因子的變化情況,進行迴顧性分析.結果 糖耐量異常組、糖尿病組化療後白細胞介素-6(IL-6),腫瘤壞死因子α(TNF-α)水平較化療前明顯增高,與血糖正常組差異有統計學意義(P＜0.01),化療後白細胞介素-10(IL-10)較化療前增高,差異有統計學意義(P＜0.05).結論 噁性腫瘤患者化療後血糖增高與細胞因子有密切的相關性.
목적 탐색악성종류화료후혈당증고여세포인자적상관성.방법 대155례악성종류환자화료후혈당정상조、당내량이상조、당뇨병조세포인자적변화정황,진행회고성분석.결과 당내량이상조、당뇨병조화료후백세포개소-6(IL-6),종류배사인자α(TNF-α)수평교화료전명현증고,여혈당정상조차이유통계학의의(P＜0.01),화료후백세포개소-10(IL-10)교화료전증고,차이유통계학의의(P＜0.05).결론 악성종류환자화료후혈당증고여세포인자유밀절적상관성.
Objective To explore the correlation between the increasing of blood glucose and cytokines in malignant tumor patients after chemotherapy.Methods According to the blood glucose after chemotherapy,155 cases of malignant tumor patient were divided into 3 groups:euglycemia group,IGT(impaired glucose tolerance)group and DM(diabetes mellitus)group.The variance of cytokines in the 3 groups were analyzed.Results Compared with pre-chemotherapy,IL-6,TNF-αincreased greatly in IGT group and DM group,while IL-10 decreased greatly.The statistical difference were obvious compared with euglycemia group.Conclusion There are close correlation between the increasing of blood glucose and cytokines in malignant tumor patients after chemotherapy.
