CAJ | 학술논문

目的研究心脏外科术后中心静脉导管相关感染(CRI)、导管相关性菌血症(CRB)的发生率和菌群分布状况,以及CRI的危险因素,为临床科学管理中心静脉导管,降低CRI、CRB的发病率提供有益的参考.方法自2005年1月至2005年12月共随机选取在心脏外科手术治疗的300例患者留置的中心静脉导管进行尖端细菌培养,同时进行血培养.结果 300例中35例(11.7%)发生CBI,CBB 5例(1.7%).病原菌菌群分布:革兰阳性球菌占54.3%,革兰阴性杆菌占34.3%.真菌占11.4%.前5位致病菌分别为:表皮葡萄球茵、金黄色葡萄球菌、肺炎克雷白杆菌、铜绿假单胞杆茵、白色念珠菌.CRl、CRB的危险因素包括:原发疾病种类、穿刺置管部位、中心静脉导管留置时间等.中心静脉导管留置时间>6d,感染率明显增加.结论 CBI、CBB是留置中心静脉导管最严重的并发症,旱期诊断、及时合理应用抗生素对降低病死率具有重要的意义.
목적 연구심장외과술후중심정맥도관상관감염(CRI)、도관상관성균혈증(CRB)적발생솔화균군분포상황,이급CRI적위험인소,위림상과학관리중심정맥도관,강저CRI、CRB적발병솔제공유익적삼고.방법 자2005년1월지2005년12월공수궤선취재심장외과수술치료적300례환자류치적중심정맥도관진행첨단세균배양,동시진행혈배양.결과 300례중35례(11.7%)발생CBI,CBB 5례(1.7%).병원균균군분포:혁란양성구균점54.3%,혁란음성간균점34.3%.진균점11.4%.전5위치병균분별위:표피포도구인、금황색포도구균、폐염극뢰백간균、동록가단포간인、백색념주균.CRl、CRB적위험인소포괄:원발질병충류、천자치관부위、중심정맥도관류치시간등.중심정맥도관류치시간>6d,감염솔명현증가.결론 CBI、CBB시류치중심정맥도관최엄중적병발증,한기진단、급시합리응용항생소대강저병사솔구유중요적의의.
Objective To investigate the pathogen culturing of the catheter related infection(CRI),cathe-ter related bloodstram infection(CRB)and risk factors after central venous catheter(CVC)of cardiovascular surgery in order to provide the beneficial reference.Methods From Jan 2005 to Dec 2005,a total of 300 cases central ve-nous cathers were determined,and the cusp of the catheters was determined by bacteria cultivation,and blood bacte-ria cultivation.Results The infection happened in 35 of 300 patients with inserted central venous catheter.The cusps of CRI rate was 11.7%.CRB rate was 1.7%.54.3%pathogens were gram-positive cocci,34.3% were gram-negative bacilli,11.4% were fungi.The most common strain were Staphylococcus epidermis,Staphylococcus aureus,Klebsiella pneumoniae,Pseudomonas aeruginose,and Candiadia albicans.The infection rate increased obviously when the dwelling time>6 d.Conclusion CRI and CRB are the most severe complication of CVC,and it is important to cut down the death with the early diagnosis and applying antibiotics rationally.