CAJ | 학술논문

目的探讨颅内原发性淋巴瘤扩散加权成像(DWI)和灌注加权成像(PWI)特点.方法回顾性分析10例颅内原发性淋巴瘤的DWI表现和9例颅内原发性淋巴瘤的PWI特征,所有病例均经病理证实,并结合其病理特征与高级别(Ⅲ、Ⅳ级)星形细胞瘤作对照.结果颅内原发性淋巴瘤DWI多呈均匀高信号,肿瘤实质ADC值为(79.73±10.21)×10-5mm2/s,明显低于高级别星形细胞瘤ADC值(99.81±19.57)×10-5mm2/s(P=0.002).9例行PWI检查,颅内原发性淋巴瘤肿瘤实质最大rCBV比值为1.71±0.59,而14例高级别星形细胞瘤肿瘤实质最大rCBV比值为5.17±1.73,与高级别旱形细胞瘤比较,颅内原发性淋巴瘤呈低灌注趋势(P=0.001).结论颅内原发性淋巴瘤DWI、PWI具有一定的特征,术前行DWI、PWI有助于提高MRI对颅内原发性淋巴瘤的诊断水平.
목적 탐토로내원발성림파류확산가권성상(DWI)화관주가권성상(PWI)특점.방법 회고성분석10례로내원발성림파류적DWI표현화9례로내원발성림파류적PWI특정,소유병례균경병리증실,병결합기병리특정여고급별(Ⅲ、Ⅳ급)성형세포류작대조.결과 로내원발성림파류DWI다정균균고신호,종류실질ADC치위(79.73±10.21)×10-5mm2/s,명현저우고급별성형세포류ADC치(99.81±19.57)×10-5mm2/s(P=0.002).9례행PWI검사,로내원발성림파류종류실질최대rCBV비치위1.71±0.59,이14례고급별성형세포류종류실질최대rCBV비치위5.17±1.73,여고급별한형세포류비교,로내원발성림파류정저관주추세(P=0.001).결론 로내원발성림파류DWI、PWI구유일정적특정,술전행DWI、PWI유조우제고MRI대로내원발성림파류적진단수평.
objective To study diffusion weighted magnetic resonance imaging(DWI)and perfusion weighted magnetic resonance imaging(PWI)features of primary intracranial lymphoma.Method The DWI features were retrospectively analyzed in 10 cases of primary intracranial lymphoma proved by operation and pathology,while PWI features of 9 cases were retrospectively studied.The comparison with 21 cases of high grade(Ⅲ,Ⅳ) astrocytomas were performed in combination with their histopathological characteristics.Results The lesions of primary intracranial lymphoma usually showed high signal on DWI,and the apparent diffusion coefficient(ADC)value of primary intracranial lymphoma was(79.73±10.21)×10-5mm2/s,and the comparison with a group of high grade astrocytomas showed a statistical significance in the ADC value(99.81 ±19.57)×10-5 mm2/s(P=0.002).PWI features showed that the maximum rCBV ratio of primary intracranial lymphoma in tumor parenchyma was 1.71±0.59,while that of high grade astrocytomas was 5.17±1.73.The primary intracranial lymphoma had a tendency to have low perfusion compared with high grades astrocytomas(P=0.001).Conclusions DWI and PWI can be useful in distinguishing primary intracranial lymphoma from high grades astrocytomas.Combining with the conventional MRI appearance with DWI and PWI features can improve MRI diagnostic accuracy of primary intracranial lymphoma.