CAJ | 학술논문

目的：探讨含静脉滴注卷曲霉素方案对耐多药肺结核患者的治疗效果。方法：采用含卷曲霉素、结核清、氧氟沙星、复合利福平及吡嗪酰胺等抗结核药物方案对耐多药肺结核患者进行治疗。结果：78例耐多药肺结核患者三个月强化期结束时痰菌阴转率58.97％，治疗一年全疗程结束时痰菌阴转率为66.67％，空洞闭合率41.38％，病灶X线好转率96.20％，不良反应率17.7％。结论：含静脉滴注卷曲霉素的化疗方案对耐多药肺结核患者疗效较为显著，同时减少了肌肉注射卷曲霉素同时的局部硬结、疼痛，患者易于接受，是一组较好的耐多药肺结核患者临床治疗方案。
목적：탐토함정맥적주권곡매소방안대내다약폐결핵환자적치료효과。방법：채용함권곡매소、결핵청、양불사성、복합리복평급필진선알등항결핵약물방안대내다약폐결핵환자진행치료。결과：78례내다약폐결핵환자삼개월강화기결속시담균음전솔58.97％，치료일년전료정결속시담균음전솔위66.67％，공동폐합솔41.38％，병조X선호전솔96.20％，불량반응솔17.7％。결론：함정맥적주권곡매소적화료방안대내다약폐결핵환자료효교위현저，동시감소료기육주사권곡매소동시적국부경결、동통，환자역우접수，시일조교호적내다약폐결핵환자림상치료방안。
Objective: To evaluate the effect of chemotherapy regimen with Capreomycin Sulfate injected by intravenous dripon multi-drug resistant pulmonary tuberculosis. Methods: The tuberculosis of multi-drug resistance were treated with capre-omycin, pasinizide, ofloxacin, rifampin compound and pyrazinamide for one year. Results: The rate of sputum negative conver-sion was 58.97% and 66.67% at the three months and the end of treatment course respectively. The rate of closing cavity was41.38%. Conclusion: Capreomycin was an effective drug injected by intravenous drip for pulmonary tuberculosis with multi-drug resistance. But the pain and lump were avoided in the injecting spots of skin. The acceptability was increased for the pa-tients.