临床儿科杂志
臨床兒科雜誌
림상인과잡지
2010年
2期
120-123
,共4页
田曼%施圣云%秦铭%刘红霞%赵德育
田曼%施聖雲%秦銘%劉紅霞%趙德育
전만%시골운%진명%류홍하%조덕육
儿童%急性下呼吸道感染%病毒%病原学
兒童%急性下呼吸道感染%病毒%病原學
인동%급성하호흡도감염%병독%병원학
children%acute lower respiratory tract infection%virus%pathogen
目的 了解儿童急性下呼吸道感染病毒病原学特点.方法 采用直接免疫荧光法(DIF),对2007年9月-2009年9月住院的5 480例0～12岁下呼吸道感染患儿鼻咽分泌物进行8种病毒检测.结果 5 480例患儿中,2 710例检出至少1种病毒,总检出率49.5%.呼吸道合胞病毒(RSV)检出最多,为1 386例,占51.1%,其余,依次是偏肺病毒(hMPV)513例(18.9%),副流感病毒Ⅲ(PIVⅢ)338例(12.5%).腺病毒(ADV)192例(7.1%);流感病毒A(IFA)128例(4.7%),流感病毒B(IFB)79例(2.9%),副流感病毒Ⅰ(PIV Ⅰ)41例(1.5%),副流感病毒Ⅱ(PIV Ⅱ)33例(1.2%).6个月以下年龄组阳性率最高,为43.5%.RSV、hMPV季节性较明显,主要集中在冬春季节(11月至次年4月).肺炎、毛细支气管炎、支气管炎(伴喘息)、支气管炎(不伴喘息)和哮喘患儿病毒阳性率分别为47.4%、63.6%、50.5%、30.1%和43.5%.结论 病毒是儿童急性下呼吸道感染的主要病原.发病年龄主要在婴幼儿,其中RSV和hMPV最常见.
目的 瞭解兒童急性下呼吸道感染病毒病原學特點.方法 採用直接免疫熒光法(DIF),對2007年9月-2009年9月住院的5 480例0～12歲下呼吸道感染患兒鼻嚥分泌物進行8種病毒檢測.結果 5 480例患兒中,2 710例檢齣至少1種病毒,總檢齣率49.5%.呼吸道閤胞病毒(RSV)檢齣最多,為1 386例,佔51.1%,其餘,依次是偏肺病毒(hMPV)513例(18.9%),副流感病毒Ⅲ(PIVⅢ)338例(12.5%).腺病毒(ADV)192例(7.1%);流感病毒A(IFA)128例(4.7%),流感病毒B(IFB)79例(2.9%),副流感病毒Ⅰ(PIV Ⅰ)41例(1.5%),副流感病毒Ⅱ(PIV Ⅱ)33例(1.2%).6箇月以下年齡組暘性率最高,為43.5%.RSV、hMPV季節性較明顯,主要集中在鼕春季節(11月至次年4月).肺炎、毛細支氣管炎、支氣管炎(伴喘息)、支氣管炎(不伴喘息)和哮喘患兒病毒暘性率分彆為47.4%、63.6%、50.5%、30.1%和43.5%.結論 病毒是兒童急性下呼吸道感染的主要病原.髮病年齡主要在嬰幼兒,其中RSV和hMPV最常見.
목적 료해인동급성하호흡도감염병독병원학특점.방법 채용직접면역형광법(DIF),대2007년9월-2009년9월주원적5 480례0～12세하호흡도감염환인비인분비물진행8충병독검측.결과 5 480례환인중,2 710례검출지소1충병독,총검출솔49.5%.호흡도합포병독(RSV)검출최다,위1 386례,점51.1%,기여,의차시편폐병독(hMPV)513례(18.9%),부류감병독Ⅲ(PIVⅢ)338례(12.5%).선병독(ADV)192례(7.1%);류감병독A(IFA)128례(4.7%),류감병독B(IFB)79례(2.9%),부류감병독Ⅰ(PIV Ⅰ)41례(1.5%),부류감병독Ⅱ(PIV Ⅱ)33례(1.2%).6개월이하년령조양성솔최고,위43.5%.RSV、hMPV계절성교명현,주요집중재동춘계절(11월지차년4월).폐염、모세지기관염、지기관염(반천식)、지기관염(불반천식)화효천환인병독양성솔분별위47.4%、63.6%、50.5%、30.1%화43.5%.결론 병독시인동급성하호흡도감염적주요병원.발병년령주요재영유인,기중RSV화hMPV최상견.
Objective To elucidate the etiology feature of viral infection in hospitalized children with acute lower respiratory infection. Methods A total of 5 480 children with acute lower respiratory tract infection, hospitalized from September 2007 to September 2009, were studied. Nasopharyngeal aspirates were screened for 8 types of viruses by direct immunofluorescence (DIF) assay. Results At least one type of viral pathogen was detected in 2 710 out of 5 480 patients and the overall positive rate was 49.5%. The most common virus was RSV (51.1%), followed by hMPV (18.9%), PIVⅢ (12.5%), ADV (7.1%), IFA (4.7%), IFB (2.9%), PIV Ⅰ (1.5%) and PIV Ⅱ (1.2%). The positive rate was highest in children under 6 months (43.5%). The seasonal change of RSV, hMPV was more obvious. The peak of RSV, hMPV appeared in the winter and the spring. The prevalence of viral infection in children with pneumonia, bronchitis, asthmatic bronchitis, non asthmatic bronchitis and asthma were 47.4%、63.6%、 50.5%、 30.1% and 43.5% respectively. Conclusions Viruses are the main cause of lower respiratory tract infections in children, especially in infants and young children. RSV and hMPV were the most common viruses in these years.
