中华实验眼科杂志
中華實驗眼科雜誌
중화실험안과잡지
CHINESE JOURNAL OF EXPERIMENTAL OPHTHALMOLOGY
2011年
10期
931-935
,共5页
晶状体/人工%非球面%波前像差%对比敏感度%视力
晶狀體/人工%非毬麵%波前像差%對比敏感度%視力
정상체/인공%비구면%파전상차%대비민감도%시력
Lens/intraocular%Aspheric%Wavefront aberration%Constrast sensitivity%Visual acuity
背景 零球差非球面人工晶状体(IOL)本身不会增加IOL植入眼的球差,理论上能够改善术眼的视觉质量.目的 比较零球差非球面IOL植入眼与球面IOL植入眼的视觉功能及波前像差,分析零球差设计对IOL植入眼视觉质量的影响.方法 采用前瞻性病例对照研究设计.收集2008年12月至2009年3月在温州医学院附属眼视光医院诊断的年龄相关性白内障的患者52例80跟,按照随机数字表法将患者随机分为零球差非球面IOL组和球面IOL组,每组40眼,分别在常规白内障超声乳化术术中植入零球差非球面IOL(Akreos AO)或球面IOL.所有患者均在术前1d,术后1d、1周、1个月及3个月时进行眼科常规检查,在裂隙灯显微镜下观察术眼眼前后节情况,测量眼压,记录裸眼视力,应用Tracey波前像差仪在术前1d检查角膜前表面波前像差,术后3个月随访时检查最佳矫正远视力(LogMAR视力),行对比敏感度、焦点深度及波前像差检查,并对2组结果进行比较.结果 2组患者术前的人口基线特征比较差异均无统计学意义(P＞0.05).术后3个月零球差非球面IOL组的最佳矫正LogMAR远视力为-0.03±0.08,球面IOL组为-0.02±0.10,2组比较差异无统计学意义(t=-0.50,P=0.61)；零球差非球面IOL组术眼在暗视(12.0 c/d)及暗视+周边眩光(3.0、6.0、18.0 c/d)条件下的对比敏感度分别为12.42±13.16、42.58±24.96、30.19±25.64和3.03±5.49,球面IOL组分别为5.59+8.11、28.74±18.69、17.07±19.35和0.22±1.15,相同条件下2组比较差异均有统计学意义(P＜0.05)；零球差非球面IOL组术眼的平均焦点深度(3.48±1.07)D,球面IOL组为(3.20±0.77)D,差异无统计学意义(t=l.15,P=0.25).术后3个月在5.0 mm瞳孔分析直径下,零球差非球面IOL组的全眼球差为(0.13±0.07)μm,球面IOL组为(0.21 +0.07)μm,差异有统计学意义(t=-4.19,P=0.00),术后3个组间术眼的全眼总高阶像差、彗差及三叶草像差比较,差异均无统计学意义(P＜0.05).结论 零球差非球面IOL植入眼视觉质量明显优于球面IOL植入眼.
揹景 零毬差非毬麵人工晶狀體(IOL)本身不會增加IOL植入眼的毬差,理論上能夠改善術眼的視覺質量.目的 比較零毬差非毬麵IOL植入眼與毬麵IOL植入眼的視覺功能及波前像差,分析零毬差設計對IOL植入眼視覺質量的影響.方法 採用前瞻性病例對照研究設計.收集2008年12月至2009年3月在溫州醫學院附屬眼視光醫院診斷的年齡相關性白內障的患者52例80跟,按照隨機數字錶法將患者隨機分為零毬差非毬麵IOL組和毬麵IOL組,每組40眼,分彆在常規白內障超聲乳化術術中植入零毬差非毬麵IOL(Akreos AO)或毬麵IOL.所有患者均在術前1d,術後1d、1週、1箇月及3箇月時進行眼科常規檢查,在裂隙燈顯微鏡下觀察術眼眼前後節情況,測量眼壓,記錄裸眼視力,應用Tracey波前像差儀在術前1d檢查角膜前錶麵波前像差,術後3箇月隨訪時檢查最佳矯正遠視力(LogMAR視力),行對比敏感度、焦點深度及波前像差檢查,併對2組結果進行比較.結果 2組患者術前的人口基線特徵比較差異均無統計學意義(P＞0.05).術後3箇月零毬差非毬麵IOL組的最佳矯正LogMAR遠視力為-0.03±0.08,毬麵IOL組為-0.02±0.10,2組比較差異無統計學意義(t=-0.50,P=0.61)；零毬差非毬麵IOL組術眼在暗視(12.0 c/d)及暗視+週邊眩光(3.0、6.0、18.0 c/d)條件下的對比敏感度分彆為12.42±13.16、42.58±24.96、30.19±25.64和3.03±5.49,毬麵IOL組分彆為5.59+8.11、28.74±18.69、17.07±19.35和0.22±1.15,相同條件下2組比較差異均有統計學意義(P＜0.05)；零毬差非毬麵IOL組術眼的平均焦點深度(3.48±1.07)D,毬麵IOL組為(3.20±0.77)D,差異無統計學意義(t=l.15,P=0.25).術後3箇月在5.0 mm瞳孔分析直徑下,零毬差非毬麵IOL組的全眼毬差為(0.13±0.07)μm,毬麵IOL組為(0.21 +0.07)μm,差異有統計學意義(t=-4.19,P=0.00),術後3箇組間術眼的全眼總高階像差、彗差及三葉草像差比較,差異均無統計學意義(P＜0.05).結論 零毬差非毬麵IOL植入眼視覺質量明顯優于毬麵IOL植入眼.
배경 령구차비구면인공정상체(IOL)본신불회증가IOL식입안적구차,이론상능구개선술안적시각질량.목적 비교령구차비구면IOL식입안여구면IOL식입안적시각공능급파전상차,분석령구차설계대IOL식입안시각질량적영향.방법 채용전첨성병례대조연구설계.수집2008년12월지2009년3월재온주의학원부속안시광의원진단적년령상관성백내장적환자52례80근,안조수궤수자표법장환자수궤분위령구차비구면IOL조화구면IOL조,매조40안,분별재상규백내장초성유화술술중식입령구차비구면IOL(Akreos AO)혹구면IOL.소유환자균재술전1d,술후1d、1주、1개월급3개월시진행안과상규검사,재렬극등현미경하관찰술안안전후절정황,측량안압,기록라안시력,응용Tracey파전상차의재술전1d검사각막전표면파전상차,술후3개월수방시검사최가교정원시력(LogMAR시력),행대비민감도、초점심도급파전상차검사,병대2조결과진행비교.결과 2조환자술전적인구기선특정비교차이균무통계학의의(P＞0.05).술후3개월령구차비구면IOL조적최가교정LogMAR원시력위-0.03±0.08,구면IOL조위-0.02±0.10,2조비교차이무통계학의의(t=-0.50,P=0.61)；령구차비구면IOL조술안재암시(12.0 c/d)급암시+주변현광(3.0、6.0、18.0 c/d)조건하적대비민감도분별위12.42±13.16、42.58±24.96、30.19±25.64화3.03±5.49,구면IOL조분별위5.59+8.11、28.74±18.69、17.07±19.35화0.22±1.15,상동조건하2조비교차이균유통계학의의(P＜0.05)；령구차비구면IOL조술안적평균초점심도(3.48±1.07)D,구면IOL조위(3.20±0.77)D,차이무통계학의의(t=l.15,P=0.25).술후3개월재5.0 mm동공분석직경하,령구차비구면IOL조적전안구차위(0.13±0.07)μm,구면IOL조위(0.21 +0.07)μm,차이유통계학의의(t=-4.19,P=0.00),술후3개조간술안적전안총고계상차、혜차급삼협초상차비교,차이균무통계학의의(P＜0.05).결론 령구차비구면IOL식입안시각질량명현우우구면IOL식입안.
Background Zero spherical aberration intraocular lenses(IOL)is designed to prevent the addition of positive spherical aberration after surgery.Research indicated that some positive spherical aberration can provide better depth distance of focus and pseudoaccommodation.Objective The present study was to compare the visual function and wavefront aberrations in pseudophakic eyes with zero spherical aberration IOL and spherical IOL.Methods A prespective case-controlled study was designed.Eighty eyes of 52 patients with age-related cataract were enrolled and divided into two matched groups based on random number table method.The regular phacoemulsification was performed on the eyes,and a zero spherical aberration IOL(Akreos AO)was implanted in the test group and a spherical IOL was used in the control group(Akreos Adapt IOL).The corrected distance visual acuity(CDVA),contrast sensitivity,depth of focus and wavefront aberrations were recorded and compared at 3 months after cataract surgery between these two groups.The trail was approved by the Ethic Committee of Eye Hospital of Wenzhou Medical College,and written informed consent was obtained from each patient prior to the program.Results The clinical demography from the two groups was matched(P ＞ 0.05).There were no significant difference in the CDVA (LogM AR)(-0.03 ±0.08 versus-0.02+0.10)(t =-0.50,P =0.61)and in depth of focus(3.48± 1.07 DS versus 3.20±0.77 DS)(t =1.15,P=0.25)between the zero spherical aberration IOL group and the spherical IOL group.The contrast sensitivities under the mesopic condition at 12.0 c/d and mesopic with glare at 3.0,6.0,18.0 c/d were 12.42 ± 13.16,42.58 ±24.96,30.19± 25.64 and 3.03 ± 5.49 in the zero spherical aberration IOL group,and those in the spherical IOL group were 5.59 ± 8.11,28.74 ± 18.69,17.07 ± 19.35 and 0.22 ± 1.15 without significant differences between these two groups(P＜0.05).Under the 5.0 mm pupil analyzing zone,the spherical aberration in zero spherical aberration IOL group was(0.13 ±0.07)μm,showing a significant reduction in comparison with spherical IOL group(0.21 + 0.07 μm)(P ＜ 0.05).No evidently differences were found in total high-order aberration,coma aberration and trefoil aberration(P＞0.05),but the sphere aberration was considerably lower in the zero spherical aberration IOL group compared with spherical IOL group(t=-4.19,P＝0.00).Conclusions The visual quality of the eyes implanted zero spherical aberration IOL is significantly better than ones implanted with spherical IOL.
