中华消化外科杂志
中華消化外科雜誌
중화소화외과잡지
CHINESE JOURNAL OF DIGESTIVE SURGERY
2012年
2期
129-131
,共3页
金慧涵%季沅%张威江%华志元%陆小亮
金慧涵%季沅%張威江%華誌元%陸小亮
금혜함%계원%장위강%화지원%륙소량
胰腺肿瘤%磁共振成像%扩散加权成像
胰腺腫瘤%磁共振成像%擴散加權成像
이선종류%자공진성상%확산가권성상
Pancreatic neoplasms%Magnetic resonance imaging%Diffusion-weighted imaging
目的 探讨磁共振扩散加权成像(DWl)及相应的表观扩散系数(ADC)在胰腺癌诊断中的应用价值.方法 回顾性分析2009年3月至2011年6月无锡市第二人民医院收治的36例胰腺癌患者和30例健康志愿者的临床资料.66例受试者接受MRI检查,进行DWI扫描.胰腺癌患者的肿瘤组织和癌周组织在T1WI、T2WI及DWI图像中的信号强度比(SIR)的比较采用单因素方差分析；肿瘤组织与癌周组织的ADC值比较采用配对t检验；肿瘤组织、癌周组织分别与健康志愿者胰腺组织的ADC值比较采用独立样本t检验.结果 胰腺癌患者术前MRI检查诊断的准确性达到92％.T2WT、T1WI及DWI图像中,胰腺癌患者的SIR分别为0.203±0.190、0.399±0.201及0.579±0.291,肿瘤组织和癌周组织的信号强度在3组图像间比较,差异有统计学意义(F=5.92,6.15,6.83,P＜0.05)；患者在T1WI和DWI图像中的SIR均明显高于T2WI图像(P＜0.05),而T1WI与DWI图像SIR比较,差异无统计学意义(P＞0.05).测量患者肿瘤组织、癌周组织、健康志愿者胰腺组织的平均ADC值分别为(1.40 ±0.24)×10-3 mm2/s、(1.71±0.10) ×10-3 mm2/s、(1.73 ±0.30) ×10-3mm2/s,肿瘤组织与癌周组织、肿瘤组织与胰腺组织的ADC值比较,差异有统计学意义(t=10.54,12.08,P＜0.05).结论 DWI图像可以清晰地显示胰腺癌病灶,ADC值的测定有助于胰腺癌的诊断.
目的 探討磁共振擴散加權成像(DWl)及相應的錶觀擴散繫數(ADC)在胰腺癌診斷中的應用價值.方法 迴顧性分析2009年3月至2011年6月無錫市第二人民醫院收治的36例胰腺癌患者和30例健康誌願者的臨床資料.66例受試者接受MRI檢查,進行DWI掃描.胰腺癌患者的腫瘤組織和癌週組織在T1WI、T2WI及DWI圖像中的信號彊度比(SIR)的比較採用單因素方差分析；腫瘤組織與癌週組織的ADC值比較採用配對t檢驗；腫瘤組織、癌週組織分彆與健康誌願者胰腺組織的ADC值比較採用獨立樣本t檢驗.結果 胰腺癌患者術前MRI檢查診斷的準確性達到92％.T2WT、T1WI及DWI圖像中,胰腺癌患者的SIR分彆為0.203±0.190、0.399±0.201及0.579±0.291,腫瘤組織和癌週組織的信號彊度在3組圖像間比較,差異有統計學意義(F=5.92,6.15,6.83,P＜0.05)；患者在T1WI和DWI圖像中的SIR均明顯高于T2WI圖像(P＜0.05),而T1WI與DWI圖像SIR比較,差異無統計學意義(P＞0.05).測量患者腫瘤組織、癌週組織、健康誌願者胰腺組織的平均ADC值分彆為(1.40 ±0.24)×10-3 mm2/s、(1.71±0.10) ×10-3 mm2/s、(1.73 ±0.30) ×10-3mm2/s,腫瘤組織與癌週組織、腫瘤組織與胰腺組織的ADC值比較,差異有統計學意義(t=10.54,12.08,P＜0.05).結論 DWI圖像可以清晰地顯示胰腺癌病竈,ADC值的測定有助于胰腺癌的診斷.
목적 탐토자공진확산가권성상(DWl)급상응적표관확산계수(ADC)재이선암진단중적응용개치.방법 회고성분석2009년3월지2011년6월무석시제이인민의원수치적36례이선암환자화30례건강지원자적림상자료.66례수시자접수MRI검사,진행DWI소묘.이선암환자적종류조직화암주조직재T1WI、T2WI급DWI도상중적신호강도비(SIR)적비교채용단인소방차분석；종류조직여암주조직적ADC치비교채용배대t검험；종류조직、암주조직분별여건강지원자이선조직적ADC치비교채용독립양본t검험.결과 이선암환자술전MRI검사진단적준학성체도92％.T2WT、T1WI급DWI도상중,이선암환자적SIR분별위0.203±0.190、0.399±0.201급0.579±0.291,종류조직화암주조직적신호강도재3조도상간비교,차이유통계학의의(F=5.92,6.15,6.83,P＜0.05)；환자재T1WI화DWI도상중적SIR균명현고우T2WI도상(P＜0.05),이T1WI여DWI도상SIR비교,차이무통계학의의(P＞0.05).측량환자종류조직、암주조직、건강지원자이선조직적평균ADC치분별위(1.40 ±0.24)×10-3 mm2/s、(1.71±0.10) ×10-3 mm2/s、(1.73 ±0.30) ×10-3mm2/s,종류조직여암주조직、종류조직여이선조직적ADC치비교,차이유통계학의의(t=10.54,12.08,P＜0.05).결론 DWI도상가이청석지현시이선암병조,ADC치적측정유조우이선암적진단.
Objective To investigate the value of diffusion weighted magnetie resonance imaging and apparent diffusion coefficient (ADC) value in the diagnosis of pancreatic cancer.Methods The clinical data of 36 patients with pancreatie cancer who were admitted to the Wuxi No.2 People's Hospital from March 2009 to June 2011 were retrospectively analyzed,and the clinical data of 30 healthy volunteers were collected.All candidates received diffusion weighted magnetie resonance imaging examination.The signal intensity ratios ( SIRs ) of the cancer and the pericancerous tissues in the T1 weighted-images (T1WI),T2 weighted-images (T2WI) and diffusion weighted-images (DWI) were compared by using one-way analysis of variance.The ADC values of the cancer and the paricancerous tissues were compared using the paired t test.The differences of the ADC values of the cancer and pericancerous tissues compared with those of healthy individuals were analyzed using an independent sample t test.Results The accuracy rate of preoperative magnetic resonance imaging examination was 92％.The relative SIRs were 0.203 ± 0.190 in the T2 WI,0.399 ± 0.201 in the T1 WI and 0.579 ± 0.291 in the DWI,respectively,with no significant differences across the 3 kinds of images (F=5.92,6.15,6.83,P ＜ 0.05 ),while SIRs of the T1 WI and DWI were significantly higher than that of the T2 WI ( P ＜ 0.05 ).There was no significant difference in SIRs when comparing T1 WI and DWI ( P ＞ 0.05 ).The mean ADC values of the cancer and pericancerous tissues of the pancreatic cancer patients and the pancreatic tissues of healthy individuals were (1.40±0.24) ×10 3 mm2/s,(1.71 ±0.10) ×10-3 mm2/s and (1.73±0.30) ×10-3 mm2/s,respectively,with significant differences across the 3 modes of images (t =10.54,12.08,P ＜ 0.05).Conclusion DWI can show high quality images of the lesions,and ADC value is helpful in the diagnosis of pancreatic cancer.
