中华临床感染病杂志
中華臨床感染病雜誌
중화림상감염병잡지
CHINESE JOURNAL OF CLINICAL INFECTIOUS DISEASES
2011年
6期
352-354
,共3页
丁贤君%李世波%黎运呈%杨喆娟%李绍佐%刘华生%林志益%黄建荣
丁賢君%李世波%黎運呈%楊喆娟%李紹佐%劉華生%林誌益%黃建榮
정현군%리세파%려운정%양철연%리소좌%류화생%림지익%황건영
胆汁酸类和盐类%炎症%慢性肝病
膽汁痠類和鹽類%炎癥%慢性肝病
담즙산류화염류%염증%만성간병
Bile acids and salts%Inflammation%Chronic liver disease
目的 研究血清总胆汁酸(TBA)水平与慢性肝病患者肝组织炎症分级间的量化关系.方法 用循环酶法检测172例各类慢性肝病患者血清TBA水平,并进行肝组织病理活检,以确定炎症分级.采用SPSS12.0软件包分析TBA与肝组织炎症分级之间的量化对应关系.结果 血清TBA水平与肝组织炎症分级呈正相关(r=0.275,P＜0.01)；当TBA达到20 μmol/L时,肝组织炎症分级达到G2水平.结论 血清TBA水平在评估慢性肝病患者肝组织炎症分级方面具有重要意义.
目的 研究血清總膽汁痠(TBA)水平與慢性肝病患者肝組織炎癥分級間的量化關繫.方法 用循環酶法檢測172例各類慢性肝病患者血清TBA水平,併進行肝組織病理活檢,以確定炎癥分級.採用SPSS12.0軟件包分析TBA與肝組織炎癥分級之間的量化對應關繫.結果 血清TBA水平與肝組織炎癥分級呈正相關(r=0.275,P＜0.01)；噹TBA達到20 μmol/L時,肝組織炎癥分級達到G2水平.結論 血清TBA水平在評估慢性肝病患者肝組織炎癥分級方麵具有重要意義.
목적 연구혈청총담즙산(TBA)수평여만성간병환자간조직염증분급간적양화관계.방법 용순배매법검측172례각류만성간병환자혈청TBA수평,병진행간조직병리활검,이학정염증분급.채용SPSS12.0연건포분석TBA여간조직염증분급지간적양화대응관계.결과 혈청TBA수평여간조직염증분급정정상관(r=0.275,P＜0.01)；당TBA체도20 μmol/L시,간조직염증분급체도G2수평.결론 혈청TBA수평재평고만성간병환자간조직염증분급방면구유중요의의.
Objective To investigate the correlation of serum total bile acid (TBA) levels with the inflammation grades of liver tissue in chronic liver diseases.Methods Cyclophorase assay was used to detect the serum TBA levels in 172 patients with various chronic liver diseases,and the inflammation grades of liver tissue were determined by liver biopsy.The correlation between serum TBA levels and the inflammation grades of liver tissue was evaluated using SPSS 12.0 software.Results Serum TBA level was positively correlated with the inflammation grade of liver tissue ( r =0.275,P ＜ 0.01 ).The inflammation grade reached G2 when serum TBA was 20 μmol/L.Conclusion Serum TBA level may be useful for evaluating the inflammation grade of liver tissue in chronic liver diseases.
