CAJ | 학술논문

目的评价SPECT/CT显像在脊柱病变鉴别诊断中的应用价值.方法对53例99Tcm-MDP全身骨显像脊柱呈放射性浓聚患者进行SPECT/CT显像,获得SPECT、CT及两者的融合图像.所有病灶均以病理学诊断及6个月以上的影像学随访为最终诊断结果,计算SPECT/CT融合图像的诊断效能.结果 SPECT/CT骨显像诊断骨转移肿瘤的灵敏度为96.00%(24/25),特异性为96.43%(27/28),准确性为96.23%(51/53),假阳性率为3.57%(1/28),假阴性率为4.00%(1/25),阳性预测值为96.00%(24/25),阴性预测值为96.43%(27/28).对脊柱浓聚灶诊断非转移性骨病变的灵敏度为96.43%(27/28),特异性为96.00%(24/25),准确性为96.23%(51/53),假阳性率为4.00%(1/25),假阴性率为3.57%(1/28),阳性预测值为96.43%(27/28),阴性预测值为96.00%(24/25).结论 SPECT/CT同机融合显像结合了CT的解剖定位功能与99Tcm-MDP骨显像的高灵敏度,可提高诊断的特异性和准确性,有助于对脊柱病变的鉴别诊断.
목적 평개SPECT/CT현상재척주병변감별진단중적응용개치.방법 대53례99Tcm-MDP전신골현상척주정방사성농취환자진행SPECT/CT현상,획득SPECT、CT급량자적융합도상.소유병조균이병이학진단급6개월이상적영상학수방위최종진단결과,계산SPECT/CT융합도상적진단효능.결과 SPECT/CT골현상진단골전이종류적령민도위96.00%(24/25),특이성위96.43%(27/28),준학성위96.23%(51/53),가양성솔위3.57%(1/28),가음성솔위4.00%(1/25),양성예측치위96.00%(24/25),음성예측치위96.43%(27/28).대척주농취조진단비전이성골병변적령민도위96.43%(27/28),특이성위96.00%(24/25),준학성위96.23%(51/53),가양성솔위4.00%(1/25),가음성솔위3.57%(1/28),양성예측치위96.43%(27/28),음성예측치위96.00%(24/25).결론 SPECT/CT동궤융합현상결합료CT적해부정위공능여99Tcm-MDP골현상적고령민도,가제고진단적특이성화준학성,유조우대척주병변적감별진단.
Objective To evaluate the value of SPECT/CT in differentiating malignancy from benign spinal disease. Methods Fifty-three patients with foci of abnormally increased uptake in the spine detected by 99Tcm-MDP planar whole body bone scan subsequently underwent bone SPECT/CT. The final diagnosis was determined by pathological examination or clinical follow-up ( ≥6 months), which was applied to calculate the diagnostic efficacy of bone SPECT/CT. Results A total of 25 patients were confirmed to have bone malignancy. The diagnostic sensitivity, specificity, accuracy, false positive rate, false negative rate, positive predictive value and negative predictive value for 99Tcm-MDP bone SPECT/CT were 96.00% (24/25), 96.43% (27/28), 96.23% (51/53), 3.57% ( 1/28), 4.00% ( 1/25), 96.00% (24/25) and 96.43% (27/28), respectively. Conclusion 99Tcm-MDP bone SPECT/CT imaging provides good clinical value for the differential diagnosis of spinal diseases.