肿瘤研究与临床
腫瘤研究與臨床
종류연구여림상
CANCER RESEARCH AND CLINIC
2011年
5期
354-356
,共3页
miRNA%卵巢肿瘤%基因表达调控
miRNA%卵巢腫瘤%基因錶達調控
miRNA%란소종류%기인표체조공
microRNAs%Ovarian neoplasms%Gene expression regulation
微小RNA(micro-RNA,即miRNA)是长约21～23nt的非编码短链RNA,是基因表达的转录后调节因子,通过与靶miRNA特异的碱基配对,引起靶miRNA降解或翻译抑制.近年研究表明miRNA在肿瘤的发生和发展中起着重要作用.
微小RNA(micro-RNA,即miRNA)是長約21～23nt的非編碼短鏈RNA,是基因錶達的轉錄後調節因子,通過與靶miRNA特異的堿基配對,引起靶miRNA降解或翻譯抑製.近年研究錶明miRNA在腫瘤的髮生和髮展中起著重要作用.
미소RNA(micro-RNA,즉miRNA)시장약21～23nt적비편마단련RNA,시기인표체적전록후조절인자,통과여파miRNA특이적감기배대,인기파miRNA강해혹번역억제.근년연구표명miRNA재종류적발생화발전중기착중요작용.
MicroRNA(miRNA)constitute a large family of small,approximately 21 to 23 nucleotide-long,non-coding RNA that is a key post-transcriptional regulators of gene expression.By base pairing to mRNA,miRNA mediate translational repression or miRNA degradation.The recent study find that miRNA play an important role in carcinogenesis.Here is a reviews of the research advances of miRNA and ovarian cancer.
