CAJ | 학술논문

体外诱导骨髓基质干细胞分化为神经细胞已经成为神经科学研究的热点之一.目前在某些实验条件下,组织特异性的干细胞在组织和器官中能衍生为各种细胞谱系.已经有撤道称骨髓基质细胞能衍生为骨骼细胞、胃贲门细胞、椭圆形肝细胞、神经胶质细胞和神经元样细胞.因此,通过资料研究分析出生后的骨髓细胞被诱导增殖进而分化为神经胶质细胞和神经元细胞,对其转化的特征作出探讨.
체외유도골수기질간세포분화위신경세포이경성위신경과학연구적열점지일.목전재모사실험조건하,조직특이성적간세포재조직화기관중능연생위각충세포보계.이경유철도칭골수기질세포능연생위골격세포、위분문세포、타원형간세포、신경효질세포화신경원양세포.인차,통과자료연구분석출생후적골수세포피유도증식진이분화위신경효질세포화신경원세포,대기전화적특정작출탐토.
In vitro differentiation of bone marrow stromal stem cells (BMSCs) into neural cells has been a hot study in neuroscience. Presently, under some experimental conditions, tissue-specific stem cells have been shown to give rise to cell lineages not normally found in the organ or tissue of residence. BMSCs have been reported to generate skeletal cells, gastric cardiac cells, oval hepatocytes, as well as glia and neuron-like cells. Cells from postnatal bone marrow were induced to proliferate and differentiate into gila and neurons. The present study explored the characteristics of its transformation.